Hydrogen Research Study
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Human clinical evidenceHuman Clinical StudyOther or not reported

Clinical Performance of Zirconia Veneers Bonded with MDP-Containing Polymeric Adhesives: A One-Year Randomized Controlled Trial.

Viet Anh Nguyen, Truong Nhu Ngoc Vo, Minh Son Tong, Thi Nhu Trang Nguyen, Thu Tra Nguyen · Polymers · 2025

Research-use notice

Independent study record

Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

H2HUBB Research Library branded molecular hydrogen research image
Primary topic Molecular Hydrogen Overview
Evidence type Human clinical evidence
Publication type Human Clinical Study
Hydrogen method Other or not reported

H2HUBB TAKEAWAY

In Fifty-two patients were treated with either translucent zirconia or lithium disilicate veneers, and restorations were bonded using light-cured resin-based adhesives, similarly, the PPD measurements also showed no significant differences between the study groups at any time point ( p > 0.05) and no significant changes within each ceramic type over the follow-up period ( p > 0.05) ( Table 5 ). These findings add human evidence that helps define the outcomes that did and did not change with molecular hydrogen in this study.

What the Findings Mean

H2HUBB reviewed how molecular hydrogen affected the outcomes measured in Fifty-two patients were treated with either translucent zirconia or lithium disilicate veneers, and restorations were bonded using light-cured resin-based adhesives. Similarly, the PPD measurements also showed no significant differences between the study groups at any time point ( p > 0.05) and no significant changes within each ceramic type over the follow-up period ( p > 0.05) ( Table 5 ).

What the Researchers Studied

The researchers studied Fifty-two patients were treated with either translucent zirconia or lithium disilicate veneers, and restorations were bonded using light-cured resin-based adhesives. The study used a randomized, double-blind human clinical trial. The comparison condition was control condition or baseline measurements.

What Effects Did Molecular Hydrogen Have?

This randomized, double-blind controlled clinical trial aimed to evaluate the one-year clinical performance of zirconia veneers etched with a hydrofluoric-nitric acid mixture and bonded using a 10-methacryloyloxydecyl dihydrogen phosphate (MDP) containing polymeric adhesive system, compared to lithium disilicate veneers. Similarly, the PPD measurements also showed no significant differences between the study groups at any time point ( p > 0.05) and no significant changes within each ceramic type over the follow-up period ( p > 0.05) ( Table 5 ). The authors concluded that this randomized, double-blind controlled clinical trial supports the short-term clinical viability of acid-etched zirconia laminate veneers as a comparable alternative to lithium disilicate veneers.

Why These Findings Matter

This publication adds useful evidence about where molecular hydrogen did and did not change the measured outcomes, helping define the larger therapeutic evidence base.

How Strong Is This Evidence?

This is human clinical evidence from a randomized, double-blind human clinical trial. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.

Technical Study Details

H2HUBB classifies this publication as human clinical study with human clinical evidence. The research population or model was Fifty-two patients were treated with either translucent zirconia or lithium disilicate veneers, and restorations were bonded using light-cured resin-based adhesives. The reported sample size was 2. The study used a randomized, double-blind human clinical trial.

Limitations and Safety

No separate limitations or safety findings were identified in the current-study source text available to H2HUBB.

Original Study and H2HUBB Research Context

H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.