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Standards

PERFORMANCE STANDARDS

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For nearly a decade we have tested and continue to test and run analysis on a wide array of hydrogen products. This extensive and in-depth testing, along with working with engineers centered on hydrogen, has allowed us to develop some key performance standards for H2 products. This page only highlights the simple and ground-level standards by which we determine what to recommend. This list does not necessarily reflect all of the standards against which we test hydrogen devices. We feel it’s necessary to share these essential standards with the public, so it is aware of what to look for when comparing products. Our performance standards  coincide with the standards set forth by IHSA (International Hydrogen Standards Association). 

hydrogen infusion machines (HIMs)

These H2 water systems are normally flow through devices that utilize PEM/SPE membrane technology. This allows these devices to infuse the source water with pure hydrogen gas without altering the pH of  water.

  • Must produce 0.8 mg/L (ppm) consistently
  • Water flow rate must be at least 1 liter/minute
  • Must produce 0.8~1 mg H2/minute
  • Must allow individuals to ingest the therapeutic target level of 1~3 mg of H2 per day by drinking 2 liters or less.

Batch Pressurized chamber HIMs

The batch pressurized chamber H2 water system (or BPC-HIM) connects to either an external water source or can be supplied with a water bottle (2~5 gal). These systems also utilize PEM/SPE membrane technology to produce pure H2 gas to be infused into the water without altering the pH of  water. BPC-HIMs produce a batch of hydrogen-rich water ranging in a volume size of 2~5 Ls of water that can be dispensed on demand. These systems normally take 15~30 mins to process a batch but typically result in high H2 levels (2~5 ppm) due to the increased pressure of the water chamber.
  • Must produce 1.6 mg/L (ppm) or above consistently
  • Dispensing flow rate must be 1 liter/minute or above
  • Must produce 0.8~1 mg H2/minute
  • Must allow individuals to ingest the therapeutic target level of 1~3 mg of H2 per day by drinking 1 liter or less.
  • No longer than 45 minutes to produce a batch

H2 effervescent tablets

H2 tablets use elemental magnesium to produce hydrogen gas in water. These tablets can produce great levels of dissolved H2 if used properly. They are great for ingesting hydrogen while traveling or on the run.

H2 tablets create hydrogen gas via the reaction of magnesium to water as follows:

Mg + 2H2O => Mg(OH)2 + H2

  • Must produce 0.8 mg/L (ppm) consistently
  • Water must remain palatable
  • Must allow individuals to ingest the therapeutic target of 1~3 mg of H2 per day by drinking 1 liter or less

Portable hydrogen water generators

Portable hydrogen water generators are small battery-operated devices that produce hydrogen water on demand in the range of 250~500 ml (8~16 oz). These system require the use of filtered water, and most designs incorporate PEM/SPE technology. 

  • Must provide 0.8 mg of H2 within serving size (e.g. two bottles per day) and not exceeding 1 liter of water (33.8 oz)
  • Must not contaminate drinking water with Chlorine
  • Must not contaminate drinking water with Ozone
  • Cycle time no longer than 15 minutes

Pure Hydrogen Inhalation Devices​

These devices use distilled water and PEM/SPE technology to produce pure hydrogen gas for inhalation. The use of distilled water eliminates the possibility of adding contaminants to the inhaled gas.

  • Must produce at least 120 ml/minute of H2
  • At minimum 4N H2 gas purity (99.99)
  • Include some form of H2 gas filtration
  • Include some form of safety device

oxy-Hydrogen inhalation devices

Oxy-Hydrogen inhalation units use water electrolysis to produce Oxygen and Hydrogen for inhalation. 

  • Must produce 2~4 % of H2 at typical resting breathing rates (i.e. 120~240 ml/min)
  • Include some form of H2 gas filtration
  • Include some form of safety device
  • Must use H2HUBB approved electrolytes (i.e. NaOH)

Pre-packaged hydrogen water

This type of hydrogen product comes ready to drink from the manufacture.The dissolved hydrogen can be placed into pure water or flavored water. Shelf-life of a year or more is achieved using aluminum cans.

  • Must have adequate packaging (i.e. Aluminum can)
  • Must contain 0.4 mg of H2 per can or more (i.e. 1.6ppm/8.3 oz)
  • Must allow individuals to intake a therapeutic amount of 0.8~1 mg of H2 per day (2 cans or under)

hydrogen water pitchers

Hydrogen water pitchers primarily utilize PEM/SPE technology to produce hydrogen gas. These systems normally hold 1~2 liters of water in their reservoir. These units typically have a cycle time of 10~45 mins during which hydrogen gas is bubbled into the water.

  • Must produce 0.8 mg/L (ppm) consistently
  • Must provide 0.8 mg of H2 within reservoir volume size (e.g. 0.8 mg/L x 1.0 L = 0.8 mg of H2)
  • Must not contaminate drinking water with Chlorine
  • Must not contaminate drinking water with Ozone
  • Must allow individuals to ingest the therapeutic target level of 1~3 mg of H2 per day

Water Ionizers

Water Ionizers use water electrolysis to produce alkaline and acidic waters. The alkaline water will contain varying levels of dissolved H2 depending on source water conditions. This is due to the fact that water ionizers are extremely dependent on source water conductivity (I.e. minerals in your source water; Mg2+, Ca2+, K+, Na+, etc) for producing hydrogen water.
  • Must produce 0.8 mg/L (ppm) consistently
  • Water flow rate must be at least 1 liter/minute
  • Must produce 0.8~1 mg H2/minute
  • The hydrogen water must remain below 9.5 pH while providing H2HUBB's minimum dissolved H2 concentration standard
  • Source water conditions must be adequate for efficient water electrolysis (tds above 100 ppm)
  • Must allow individuals to ingest the therapeutic target level of 1~3 mg of H2 per day by drinking 2 liters or less.
H2 Bath Device

Hydrogen Bath Products

Hydrogen bath products and/or systems are designed to infuse bath water (whole baths, foot baths, etc.) with hydrogen gas. These products include powders, tablets and electrolytic devices.

  • Must produce a minimum of 0.3 mg/L (ppm).
  • Minimum mg/L (ppm) concentration must be achieved in a minimum of 3L of water.
  • The device or product must generate the minimum therapeutic concentration of H2 at typical bath water temperatures (95-100F)
  • The device or product must generate the minimum therapeutic concentration of H2 within 20 mins.
  • Must have adequate safety features.

Portable hydrogen Inhalation device

These devices generally use distilled water and PEM/SPE technology to produce pure hydrogen gas. They deliver either pure H2 or H2 mixed with air for H2 inhalation. The use of distilled water eliminates the possibility of adding contaminants to the inhaled gas.
  • Must produce at least 50 mL/minute of H2 (50 mL/min ≈ >1% H2 at resting breathing rates (4-6 L/min)
  • At minimum 4N H2 gas purity (99.99)
  • Include some form of H2 gas filtration
  • Include some form of safety device
  • See absolute minimum flow rate (mL/min) standard below for further details

Smaller Inhalation Units

There have been a number of studies demonstrating that 1-1.3% (vol/vol) of H2 may offer therapeutic potential. That is equivalent to 50-78 mL/min @ 5‐6L/min gas exchange or ventilation minute. For this reason, we made this the absolute minimum threshold or standard for our recommendation for smaller inhalation units (e.g. portable devices).

“As demonstrated by studies, 1–4 % (v/v) H2 gas delivered through inhalation is effective as a treatment for I/R injury [72]” https://www.sciencedirect.com/science/article/pii/S0753332220307824

“from the National Cerebral and Cardiovascular Center (Osaka, Japan), which verified that inhalation of 1–4% hydrogen gas alleviated tissue damage and reduced the infarct size.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891106/

“They also showed that this aberrant oxidization of phospholipid was observed with a low concentration of hydrogen (at least 1.3 %), suggesting that the biological effects of hydrogen could be explained by the aberrant oxidation of phospholipid under hydrogen exposure. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610055/

“In addition to hydrogen administration in water or saline, hydrogen-containing gas (HCG) (1.3% hydrogen + 20.8% oxygen + 77.9% nitrogen) is also a viable option.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600250/

“For example, one group reported that inhalation of 1% H2 gas or drinking H2 water attenuated the cisplatin-induced nephrotoxicity, mortality, and loss of body weight.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600250/

Until IHSA (http://www.intlhsa.org/), develops H2 inhalation standards we have to set minimum standards based on the entirety of the current data. This minimum threshold or standard only applies for legitimate portable inhalation units or smaller inhalation units. Any recommended product that is approved at this mL/min minimum standard will be listed at a Tier 1 status. This minimum standard will not apply for larger or flagship H2 inhalation systems, their minimum standard will remain 120 mL/min. Lastly, this standard is subject to change as the biomedical research of hydrogen progresses or if IHSA develops H2 inhalation standards.

Hydrogen Goggles

Hydrogen goggles are designed to administer H2 to the eyes. Typically, these goggles are provided as an accessory item for H2 inhalation units. They generally are accompanied with some form of tubing to attach the goggles to the inhalation system, so that hydrogen can be applied to the eyes.
  • H2 goggles must fit securely with minimal to no air gaps.
  • H2 goggles must be used with PEM/SPE technology.
  • The H2 gas flow rate supplied to the goggles must be at least 10 mL/min.
  • The session time-frame must be at least 30 minutes.

Methods to Produce

HYDROGEN

There are many ways to produce hydrogen, but how exactly to they work? With all the misconceptions out there, it is important to know the difference.

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Think your H2 product can perform past our standards? We would LOVE to test your product! Contact us today!