Effect of hydrogen-rich water on oxidative stress, liver function, and viral load in patients with chronic hepatitis B.
Chunxiang Xia, Wenwu Liu, Dongxiao Zeng, Liyao Zhu, Xiaoli Sun, Xuejun Sun · Clinical and translational science · 2013
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In 60 patients, after treatment, the oxidative stress remained unchanged in routine treatment group, but markedly improved in hydrogen treatment group. These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence oxidative-stress regulation in healthy adults.
What the Findings Mean
H2HUBB reviewed how hydrogen-rich water affected the outcomes measured in 60 patients. After treatment, the oxidative stress remained unchanged in routine treatment group, but markedly improved in hydrogen treatment group.
What the Researchers Studied
The researchers studied 60 patients. The study used a randomized human clinical trial.
What Effects Did Molecular Hydrogen Have?
1800 mL hydrogen-rich water per reported dose; dissolved H₂ concentration was not reported in the available source text, so H2HUBB did not estimate milligrams of H₂. After treatment, the oxidative stress remained unchanged in routine treatment group, but markedly improved in hydrogen treatment group. The authors concluded that HRW significantly attenuates oxidative stress in CHB patients, but further study with long-term treatment is required to confirm the effect of HRW on liver function and HBV DNA level.
Why These Findings Matter
These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence oxidative-stress regulation in healthy adults and contribute to the growing body of molecular-hydrogen research.
How Strong Is This Evidence?
This is human clinical evidence from a randomized human clinical trial. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.
Technical Study Details
H2HUBB classifies this publication as human clinical study with human clinical evidence. The research population or model was 60 patients. The study used a randomized human clinical trial. The hydrogen delivery method was hydrogen-rich water. H2HUBB translates the reported hydrogen dose as 1800 mL hydrogen-rich water per reported dose; dissolved H₂ concentration was not reported in the available source text, so H2HUBB did not estimate milligrams of H₂.
Limitations and Safety
No separate limitations or safety findings were identified in the source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.