Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model
Tamura Tomoyoshi, Sano Motoaki, Matsuoka Tadashi, Yoshizawa Joe, Yamamoto Ryo, Katsumata Yoshinori, Endo Jin, Homma Koichiro, Kajimura Mayumi, Suzuki Masaru, Kobayashi Eiji, Sasaki Junichi · Shock · 2020
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Independent study record
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The publication “Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model” is organized in H2HUBB under the research focus hydrogen inhalation blood pressure study 2020 tomoyoshi. The publication is cited as Tamura Tomoyoshi, Sano Motoaki, Matsuoka Tadashi, Yoshizawa Joe, Yamamoto Ryo, Katsumata Yoshinori, Endo Jin, Homma Koichiro, Kajimura Mayumi, Suzuki Masaru, Kobayashi Eiji, Sasaki Junichi, Shock, 2020. This animal study examined Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: H2 inhalation after shock stabilized hemodynamics and improved survival rates in an HS/R model independent of XOR. The therapeutic action of H2 was partially…. This is an automated editorial draft based on the abstract and requires source review before publication.
Hydrogen inhalation blood pressure study 2020 tomoyoshi overview
Hydrogen gas (H2) inhalation during hemorrhage stabilizes post-resuscitation hemodynamics, improving short-term survival in a rat hemorrhagic shock and resuscitation (HS/R) model. However, the underlying… Animal research can identify biological effects and support future investigation, but it cannot by itself establish safety or effectiveness in humans.
Study design and hydrogen intervention
Publication type: Animal study. Evidence type: Preclinical animal evidence. Research model or population: Rat model. Blinding: Unknown. Control status: Unknown.
Delivery method: Hydrogen inhalation.
Reported findings and scientific interpretation
For this hydrogen inhalation blood pressure study 2020 tomoyoshi, the study record reports the following: The abstract reports: H2 inhalation after shock stabilized hemodynamics and improved survival rates in an HS/R model independent of XOR. The therapeutic action of H2 was partially…
These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.
How this research record was prepared
H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.
Limitations, safety, and original source
Limitations: Preclinical animal findings may not translate directly to human outcomes.
Safety: The abstract did not provide detailed safety or adverse-event information.
This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.