Association between hydrogen gas inhalation and cardiac output in an asphyxiated piglet model
Sakamoto Kosuke, Nakamura Shinji, Tsuchiya Toui, Mitsuie Tsutomu, Nakao Yasuhiro, Htun Yinmon, Yokota Takayuki, Inoue Kota, Inoue Eri, Wakabayashi Takayuki, Morimoto Aya, Koyano Kosuke, Konishi Yukihiko, Iwase Takashi, Horii Taikou, Kusaka Takashi · Scientific Reports · 2026
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

The publication “Association between hydrogen gas inhalation and cardiac output in an asphyxiated piglet model” is organized in H2HUBB under the research focus hydrogen inhalation cardiovascular health study 2026. The publication is cited as Sakamoto Kosuke, Nakamura Shinji, Tsuchiya Toui, Mitsuie Tsutomu, Nakao Yasuhiro, Htun Yinmon, Yokota Takayuki, Inoue Kota, Inoue Eri, Wakabayashi Takayuki, Morimoto Aya, Koyano Kosuke, Konishi Yukihiko, Iwase Takashi, Horii Taikou, Kusaka Takashi, Scientific Reports, 2026. This animal study examined Association between hydrogen gas inhalation and cardiac output in an asphyxiated piglet model. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. The abstract reports: The HI group (n = 10) showed a transient increase in SV and CO followed by a decline. This is an automated editorial draft based on the abstract and requires source review before publication.
Hydrogen inhalation cardiovascular health study 2026 overview
This study investigated the effects of H2 gas inhalation on cardiac function in piglets after hypoxia-ischaemia (HI). Animal research can identify biological effects and support future investigation, but it cannot by itself establish safety or effectiveness in humans.
Study design and hydrogen intervention
Publication type: Animal study. Evidence type: Preclinical animal evidence. Research model or population: Porcine model. Blinding: Unknown. Control status: Unknown.
Delivery method: Hydrogen inhalation.
Reported findings and scientific interpretation
For this hydrogen inhalation cardiovascular health study 2026, the study record reports the following: The abstract reports: The HI group (n = 10) showed a transient increase in SV and CO followed by a decline.
These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.
How this research record was prepared
H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.
Limitations, safety, and original source
Limitations: Preclinical animal findings may not translate directly to human outcomes.
Safety: The abstract did not provide detailed safety or adverse-event information.
This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.