iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice.
Xie K, Lian N, Kan Y, Yang M, Pan J, Yu Y, Yu Y · Brain research · 2020
Research-use notice
Independent study record
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The publication “iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice.” is organized in H2HUBB under the research focus hydrogen neurological study 2020 xie. The publication is cited as Xie K, Lian N, Kan Y, Yang M, Pan J, Yu Y, Yu Y, Brain research, 2020. This uncontrolled human study examined iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: The results of the H&E, and Nissl staining indicated that the CLP mice had a significant brain injury, which was characterized by aggravated pathological…. This is an automated editorial draft based on the abstract and requires source review before publication.
Hydrogen neurological study 2020 xie overview
The isobaric tags for relative and absolute quantitation (iTRAQ)-based quantitative proteomics combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis, hematoxylin and eosin (H&E) staining,… Animal research can identify biological effects and support future investigation, but it cannot by itself establish safety or effectiveness in humans.
Study design and hydrogen intervention
Publication type: Animal study. Evidence type: Preclinical animal evidence. Research model or population: Mouse model. Blinding: Unknown. Control status: Unknown.
Delivery method: Hydrogen inhalation.
Reported findings and scientific interpretation
For this hydrogen neurological study 2020 xie, the study record reports the following: The abstract reports: The results of the H&E, and Nissl staining indicated that the CLP mice had a significant brain injury, which was characterized by aggravated pathological…
These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.
How this research record was prepared
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Limitations, safety, and original source
Limitations: The abstract alone may not report all methodological limitations; full-text review is required.
Safety: The abstract did not provide detailed safety or adverse-event information.
This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.