Hydrogen Research Study
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Human clinical evidenceRandomized controlled trialHydrogen inhalation

Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection.

Ono H, Nishijima Y, Ohta S, Sakamoto M, Kinone K, Horikosi T, Tamaki M, Takeshita H, Futatuki T, Ohishi W, Ishiguro T, Okamoto S, Ishii S, Takanami H · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2017

Research-use notice

Independent study record

Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

H2HUBB Research Library branded molecular hydrogen research image
Primary topic Blood Pressure and Vascular Function
Evidence type Human clinical evidence
Publication type Randomized controlled trial
Hydrogen method Hydrogen inhalation
hydrogen inhalation research study 2017 ono research summary

The publication “Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection.” is organized in H2HUBB under the research focus hydrogen inhalation research study 2017 ono. The publication is cited as Ono H, Nishijima Y, Ohta S, Sakamoto M, Kinone K, Horikosi T, Tamaki M, Takeshita H, Futatuki T, Ohishi W, Ishiguro T, Okamoto S, Ishii S, Takanami H, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2017. This randomized controlled trial examined Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection. The abstract describes Human participants; sample size 50; hydrogen delivered as hydrogen inhalation. The abstract reports: H treatment was safe and effective in patients with acute cerebral infarction. These results suggested a potential for widespread and general application of H…. This is an automated editorial draft based on the abstract and requires source review before publication.

Hydrogen inhalation research study 2017 ono overview

Molecular hydrogen (H) acts as a therapeutic antioxidant. Inhalation of H gas (1-4%) was effective for the improvement of cerebral infarction in multiple animal… Because this is human clinical evidence, relevance depends on participant selection, controls, sample size, treatment duration, adherence, outcome measures, and replication.

Study design and hydrogen intervention

Publication type: Randomized controlled trial. Evidence type: Human clinical evidence. Research model or population: Human participants. Sample size: 50. Randomized: Yes. Blinding: Unknown. Control status: Control group reported.

Delivery method: Hydrogen inhalation.

Reported findings and scientific interpretation

For this hydrogen inhalation research study 2017 ono, the study record reports the following: The abstract reports: H treatment was safe and effective in patients with acute cerebral infarction. These results suggested a potential for widespread and general application of H…

These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.

How this research record was prepared

H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.

Limitations, safety, and original source

Limitations: The abstract alone may not report all methodological limitations; full-text review is required.

Safety: Through this randomized controlled clinical study, we assessed the safety and effectiveness of H treatment in patients with cerebral infarction in an acute stage…

This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.