Hydrogen-rich saline protects against liver injury in rats with obstructive jaundice.
Liu Q, Shen WF, Sun HY, Fan DF, Nakao A, Cai JM, Yan G, Zhou WP, Shen RX, Yang JM, Sun XJ · Liver international : official journal of the International Association for the Study of the Liver · 2010
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
The publication “Hydrogen-rich saline protects against liver injury in rats with obstructive jaundice.” is organized in H2HUBB under the research focus hydrogen-rich saline fatty liver study 2010. The publication is cited as Liu Q, Shen WF, Sun HY, Fan DF, Nakao A, Cai JM, Yan G, Zhou WP, Shen RX, Yang JM, Sun XJ, Liver international : official journal of the International Association for the Study of the Liver, 2010. This animal study examined Hydrogen-rich saline protects against liver injury in rats with obstructive jaundice. The abstract describes Rat model; sample size 56; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline attenuates BDL-induced liver damage, possibly by the reduction of inflammation and oxidative stress and the inhibition of the ERK1/2 pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Hydrogen-rich saline fatty liver study 2010 overview
In this study, we investigated the effects of hydrogen-rich saline on the prevention of liver injury induced by obstructive jaundice in rats. Animal research can identify biological effects and support future investigation, but it cannot by itself establish safety or effectiveness in humans.
Study design and hydrogen intervention
Publication type: Animal study. Evidence type: Preclinical animal evidence. Research model or population: Rat model. Sample size: 56. Blinding: Unknown. Control status: Unknown.
Delivery method: Hydrogen-rich saline. Dose or treatment amount: 5 ml.
Reported findings and scientific interpretation
For this hydrogen-rich saline fatty liver study 2010, the study record reports the following: The abstract reports: Hydrogen-rich saline attenuates BDL-induced liver damage, possibly by the reduction of inflammation and oxidative stress and the inhibition of the ERK1/2 pathway.
These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.
How this research record was prepared
H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.
Limitations, safety, and original source
Limitations: Preclinical animal findings may not translate directly to human outcomes.
Safety: The abstract did not provide detailed safety or adverse-event information.
This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.