Peritoneal lavage with hydrogen-rich saline can be an effective and practical procedure for acute peritonitis

The publication “Peritoneal lavage with hydrogen-rich saline can be an effective and practical procedure for acute peritonitis” is organized in H2HUBB under the research focus hydrogen-rich saline oxidative stress study 2021. The publication is cited as Sada Haruki, Egi Hiroyuki, Ide Kentaro, Sawada Hiroyuki, Sumi Yusuke, Hattori Minoru, Sentani Kazuhiro, Oue Naohide, Yasui Wataru, Ohdan Hideki, Surgery Today, 2021. This uncontrolled human study examined Peritoneal lavage with hydrogen-rich saline can be an effective and practical procedure for acute peritonitis. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. The abstract reports: This procedure can improve survival after sepsis through mitigating the sepsis-induced organ failure by inhibiting oxidative stress, apoptosis, and inflammatory pathways. Peritoneal lavage with…. This is an automated editorial draft based on the abstract and requires source review before publication.

Hydrogen-rich saline oxidative stress study 2021 overview

Acute peritonitis has remained a fatal disease despite of recent advances in care and treatment, including antibiotic and anticoagulant treatments. The cause of death… Because this is human clinical evidence, relevance depends on participant selection, controls, sample size, treatment duration, adherence, outcome measures, and replication.

Study design and hydrogen intervention

Publication type: Uncontrolled human study. Evidence type: Human clinical evidence. Research model or population: Human participants. Blinding: Unknown. Control status: Unknown.

Delivery method: Hydrogen-rich saline.

Reported findings and scientific interpretation

For this hydrogen-rich saline oxidative stress study 2021, the study record reports the following: The abstract reports: This procedure can improve survival after sepsis through mitigating the sepsis-induced organ failure by inhibiting oxidative stress, apoptosis, and inflammatory pathways. Peritoneal lavage with…

These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.

How this research record was prepared

H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.

Limitations, safety, and original source

Limitations: The abstract alone may not report all methodological limitations; full-text review is required.

Safety: In the second experiment, the changes in the hemodynamic state following this procedure were observed in a porcine model of abdominal sepsis to evaluate…

This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.