Peripheral endothelial function can be improved by daily consumption of water containing over 7 ppm of dissolved hydrogen: A randomized controlled trial.
Ishibashi T, Kawamoto K, Matsuno K, Ishihara G, Baba T, Komori N · PloS one · 2020
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

The publication “Peripheral endothelial function can be improved by daily consumption of water containing over 7 ppm of dissolved hydrogen: A randomized controlled trial.” is organized in H2HUBB under the research focus hydrogen water blood pressure study 2020. The publication is cited as Ishibashi T, Kawamoto K, Matsuno K, Ishihara G, Baba T, Komori N, PloS one, 2020. This randomized controlled trial examined Peripheral endothelial function can be improved by daily consumption of water containing over 7 ppm of dissolved hydrogen: A randomized controlled trial. The abstract describes Human participants; sample size 34; hydrogen delivered as hydrogen water. The abstract reports: Daily consumption of high H2 water improved the endothelial function of the arteries or arterioles assessed by the PAT test. The results suggest that…. This is an automated editorial draft based on the abstract and requires source review before publication.
Hydrogen water blood pressure study 2020 overview
Measurement of the reactive hyperemia index (RHI) using peripheral arterial tonometry (PAT) has shown benefits in the evaluation of vascular endothelial function and prediction… Because this is human clinical evidence, relevance depends on participant selection, controls, sample size, treatment duration, adherence, outcome measures, and replication.
Study design and hydrogen intervention
Publication type: Randomized controlled trial. Evidence type: Human clinical evidence. Research model or population: Human participants. Sample size: 34. Randomized: Yes. Blinding: Double-blind. Control status: Unknown.
Delivery method: Hydrogen water. Hydrogen concentration: 7 ppm. Dose or treatment amount: 3.5 mg.
Reported findings and scientific interpretation
For this hydrogen water blood pressure study 2020, the study record reports the following: The abstract reports: Daily consumption of high H2 water improved the endothelial function of the arteries or arterioles assessed by the PAT test. The results suggest that…
These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.
How this research record was prepared
H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.
Limitations, safety, and original source
Limitations: The abstract alone may not report all methodological limitations; full-text review is required.
Safety: The abstract did not provide detailed safety or adverse-event information.
This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.