Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice.
Ohsawa I, Nishimaki K, Yamagata K, Ishikawa M, Ohta S · Biochemical and biophysical research communications · 2008
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
The publication “Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice.” is organized in H2HUBB under the research focus hydrogen water cardiovascular health study 2008. The publication is cited as Ohsawa I, Nishimaki K, Yamagata K, Ishikawa M, Ohta S, Biochemical and biophysical research communications, 2008. This in vitro or cellular study examined Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: We have found that hydrogen (dihydrogen; H(2)) acts as an effective antioxidant to reduce oxidative stress [I. This is an automated editorial draft based on the abstract and requires source review before publication.
Hydrogen water cardiovascular health study 2008 overview
Here, we investigated whether drinking H(2)-dissolved water at a saturated level (H(2)-water) ad libitum prevents arteriosclerosis using an apolipoprotein E knockout mouse (apoE(-/-)), a… Laboratory and cellular research can clarify mechanisms, but it does not establish clinical benefit or reproduce the complexity of a living human system.
Study design and hydrogen intervention
Publication type: In vitro or cellular study. Evidence type: Laboratory or cellular evidence. Research model or population: Cell culture / in vitro model. Blinding: Unknown. Control status: Unknown.
Delivery method: Hydrogen water.
Reported findings and scientific interpretation
For this hydrogen water cardiovascular health study 2008, the study record reports the following: The abstract reports: We have found that hydrogen (dihydrogen; H(2)) acts as an effective antioxidant to reduce oxidative stress [I.
These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.
How this research record was prepared
H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.
Limitations, safety, and original source
Limitations: Laboratory findings may not translate directly to living organisms or clinical outcomes.
Safety: The abstract did not provide detailed safety or adverse-event information.
This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.