Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis: A Pilot Study.
Azuma T, Yamane M, Ekuni D, Kawabata Y, Kataoka K, Kasuyama K, Maruyama T, Tomofuji T, Morita M · Antioxidants (Basel, Switzerland) · 2015
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
The publication “Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis: A Pilot Study.” is organized in H2HUBB under the research focus hydrogen water oral health study 2015. The publication is cited as Azuma T, Yamane M, Ekuni D, Kawabata Y, Kataoka K, Kasuyama K, Maruyama T, Tomofuji T, Morita M, Antioxidants (Basel, Switzerland), 2015. This uncontrolled human study examined Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis: A Pilot Study. The abstract describes Human participants; sample size 6; hydrogen delivered as hydrogen water. The abstract reports: The HW group showed greater improvements in probing pocket depth and clinical attachment level than the control group at two, four and eight weeks…. This is an automated editorial draft based on the abstract and requires source review before publication.
Hydrogen water oral health study 2015 overview
Oral examinations were performed at baseline, two, four and eight weeks, and serum was obtained at these time points to evaluate oxidative stress. Because this is human clinical evidence, relevance depends on participant selection, controls, sample size, treatment duration, adherence, outcome measures, and replication.
Study design and hydrogen intervention
Publication type: Uncontrolled human study. Evidence type: Human clinical evidence. Research model or population: Human participants. Sample size: 6. Blinding: Unknown. Control status: Control group reported.
Delivery method: Hydrogen water.
Reported findings and scientific interpretation
For this hydrogen water oral health study 2015, the study record reports the following: The abstract reports: The HW group showed greater improvements in probing pocket depth and clinical attachment level than the control group at two, four and eight weeks…
These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.
How this research record was prepared
H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.
Limitations, safety, and original source
Limitations: The reported sample size was small.
Safety: The abstract did not provide detailed safety or adverse-event information.
This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.