Estimation of Molecular Hydrogen Consumption in the Human Whole Body After the Ingestion of Hydrogen-Rich Water
Shimouchi A, Nose K, Shirai M, Kondo T · Advances in experimental medicine and biology · 2012
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
Seven healthy adults were studied after they consumed hydrogen-rich water. Breath hydrogen increased rapidly and was near baseline within about an hour. The researchers reported that much of the ingested hydrogen was exhaled and that a substantial remainder was consumed or retained in the body. This small physiology study was not designed to measure a health outcome or treatment effect.
How the Study Was Conducted
Seven healthy adults ingested hydrogen-rich water, followed by serial expired-air hydrogen measurements and an estimate of hydrogen released through the skin.
How Molecular Hydrogen Was Used
Participants consumed a single hydrogen-rich-water exposure under the study protocol.
What the Researchers Found
Expired-air hydrogen peaked at about 10 minutes and declined toward baseline within about 60 minutes; the authors estimated the proportions exhaled, released through skin, and consumed or retained in the body.
Study Limitations
The report involved only seven healthy adults, used short-term physiological estimates, and did not evaluate symptoms, disease outcomes, repeated dosing, or clinical benefit.
H2HUBB Evidence Boundary
This is a small human pharmacokinetic-style physiology report. It estimates hydrogen handling after ingestion and cannot establish therapeutic effectiveness, an optimal dose, or long-term clinical outcomes.