Hydrogen Research Study
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Preclinical animal evidenceAnimal studyInjected or infused hydrogen

Beneficial effects of hydrogen gas on porcine liver reperfusion injury with use of total vascular exclusion and active venous bypass.

Matsuno N, Watanabe R, Kimura M, Iwata S, Fujiyama M, Kono S, Shigeta T, Enosawa S · Transplantation proceedings · 2014

Research-use notice

Independent study record

Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

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Primary topic Blood Pressure and Vascular Function
Evidence type Preclinical animal evidence
Publication type Animal study
Hydrogen method Injected or infused hydrogen
injected hydrogen blood pressure study 2014 research summary

The publication “Beneficial effects of hydrogen gas on porcine liver reperfusion injury with use of total vascular exclusion and active venous bypass.” is organized in H2HUBB under the research focus injected hydrogen blood pressure study 2014. The publication is cited as Matsuno N, Watanabe R, Kimura M, Iwata S, Fujiyama M, Kono S, Shigeta T, Enosawa S, Transplantation proceedings, 2014. This animal study examined Beneficial effects of hydrogen gas on porcine liver reperfusion injury with use of total vascular exclusion and active venous bypass. The abstract describes Porcine model; hydrogen delivered as injected or infused hydrogen; reported duration 60 minutes. The abstract reports: The solution containing hydrogen gas was safe and had remarkably protective effects on the porcine during liver I/R and may be applied in the…. This is an automated editorial draft based on the abstract and requires source review before publication.

Injected hydrogen blood pressure study 2014 overview

Liver ischemia/reperfusion (I/R) injury is a high risk factor in liver transplantation and it influences graft survival. One of the major events during I/R… Animal research can identify biological effects and support future investigation, but it cannot by itself establish safety or effectiveness in humans.

Study design and hydrogen intervention

Publication type: Animal study. Evidence type: Preclinical animal evidence. Research model or population: Porcine model. Blinding: Unknown. Control status: Unknown.

Delivery method: Injected or infused hydrogen. Hydrogen concentration: 5 ppm. Treatment duration: 60 minutes.

Reported findings and scientific interpretation

For this injected hydrogen blood pressure study 2014, the study record reports the following: The abstract reports: The solution containing hydrogen gas was safe and had remarkably protective effects on the porcine during liver I/R and may be applied in the…

These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.

How this research record was prepared

H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.

Limitations, safety, and original source

Limitations: Preclinical animal findings may not translate directly to human outcomes.
The intervention or follow-up period appears relatively short.

Safety: The abstract did not provide detailed safety or adverse-event information.

This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.