A basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level

The publication “A basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level” is organized in H2HUBB under the research focus molecular hydrogen hydrogen safety study 2012. The publication is cited as Ono Hirohisa, Nishijima Yoji, Adachi Naoto, Sakamoto Masaki, Kudo Yohei, Kaneko Kumi, Nakao Atsunori, Imaoka Takashi, Medical Gas Research, 2012. This uncontrolled human study examined A basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level. The abstract describes Human participants; sample size 10; reported duration 30 min. The abstract reports: H2 inhalation of at least 3% concentration for 30 min delivered enough HC, equivalent to the animal experiment levels, in the blood without compromising…. This is an automated editorial draft based on the abstract and requires source review before publication.

Molecular hydrogen hydrogen safety study 2012 overview

In animal experiments, use of molecular hydrogen ( H2) has been regarded as quite safe and effective, showing benefits in multiple pathological conditions such… Because this is human clinical evidence, relevance depends on participant selection, controls, sample size, treatment duration, adherence, outcome measures, and replication.

Study design and hydrogen intervention

Publication type: Uncontrolled human study. Evidence type: Human clinical evidence. Research model or population: Human participants. Sample size: 10. Blinding: Unknown. Control status: Unknown.

Delivery method: Other or not reported. Treatment duration: 30 min.

Reported findings and scientific interpretation

For this molecular hydrogen hydrogen safety study 2012, the study record reports the following: The abstract reports: H2 inhalation of at least 3% concentration for 30 min delivered enough HC, equivalent to the animal experiment levels, in the blood without compromising…

These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.

How this research record was prepared

H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.

Limitations, safety, and original source

Limitations: The reported sample size was small.

Safety: However, since cerebral ischemia patients are in old age group, the safety information needs to be confirmed.

This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.