[Role of hydrogen gas in regulating of poly (ADP-ribose) polymerase-1 dependent cell death in rat Schwann cells].
Yu Y, Jiao Y, Li B, Ma X, Yang T, Xie K, Yu Y · Zhonghua wei zhong bing ji jiu yi xue · 2016
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
The publication “[Role of hydrogen gas in regulating of poly (ADP-ribose) polymerase-1 dependent cell death in rat Schwann cells].” is organized in H2HUBB under the research focus molecular hydrogen inflammation immune study 2016 yu. The publication is cited as Yu Y, Jiao Y, Li B, Ma X, Yang T, Xie K, Yu Y, Zhonghua wei zhong bing ji jiu yi xue, 2016. This animal study examined [Role of hydrogen gas in regulating of poly (ADP-ribose) polymerase-1 dependent cell death in rat Schwann cells]. The abstract describes Rat model; reported duration 48 hours. The abstract reports: A small amount of AIF expression was found in the nucleus of HG+H2 group, which indicated that high glucose could promote the AIF nuclear…. This is an automated editorial draft based on the abstract and requires source review before publication.
Molecular hydrogen inflammation immune study 2016 yu overview
To investigate the protective effects and underlying molecular mechanisms of hydrogen (H2) on high glucose-induced poly (ADP-ribose) polymerase-1 (PARP-1) dependent cell death (PARthanatos) in… Animal research can identify biological effects and support future investigation, but it cannot by itself establish safety or effectiveness in humans.
Study design and hydrogen intervention
Publication type: Animal study. Evidence type: Preclinical animal evidence. Research model or population: Rat model. Blinding: Unknown. Control status: Control group reported.
Delivery method: Other or not reported. Hydrogen concentration: 0.6 mmol/L. Treatment duration: 48 hours.
Reported findings and scientific interpretation
For this molecular hydrogen inflammation immune study 2016 yu, the study record reports the following: The abstract reports: A small amount of AIF expression was found in the nucleus of HG+H2 group, which indicated that high glucose could promote the AIF nuclear…
These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.
How this research record was prepared
H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.
Limitations, safety, and original source
Limitations: Preclinical animal findings may not translate directly to human outcomes.
The intervention or follow-up period appears relatively short.
Safety: However, H2 can not only reduce DNA damage of injured cells, but also inhibit the special death process, reduce the cell toxicity, all of…
This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.