Hydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model.

The publication “Hydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model.” is organized in H2HUBB under the research focus molecular hydrogen inflammation immune study 2026. The publication is cited as Gandini L, Liu K, Passmore MR, Chan CHH, Wilson ES, Ijuin S, Milani A, Hyslop K, White N, Perera B, Obonyo N, Bouquet M, Li Bassi G, Fraser JF, Suen JY, ASAIO journal (American Society for Artificial Internal Organs : 1992), 2026. This uncontrolled human study examined Hydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model. The abstract describes Human participants; sample size 4; reported duration 6 hours. The abstract reports: Hydrogen exposure significantly reduced collagen (p = 0.01), TRAP-6 (p = 0.04), and ADP-induced (p = 0.04) platelet aggregation and showed a trend toward…. This is an automated editorial draft based on the abstract and requires source review before publication.

Molecular hydrogen inflammation immune study 2026 overview

This ex vivo study investigated whether ECMO could serve as an effective vehicle for hydrogen delivery. Laboratory and cellular research can clarify mechanisms, but it does not establish clinical benefit or reproduce the complexity of a living human system.

Study design and hydrogen intervention

Publication type: In vitro or cellular study. Evidence type: Laboratory or cellular evidence. Research model or population: Ex vivo extracorporeal membrane oxygenation model. Sample size: 4. Blinding: Unknown. Control status: Unknown.

Delivery method: Other or not reported. Treatment duration: 6 hours.

Reported findings and scientific interpretation

For this molecular hydrogen inflammation immune study 2026, the study record reports the following: The abstract reports: Hydrogen exposure significantly reduced collagen (p = 0.01), TRAP-6 (p = 0.04), and ADP-induced (p = 0.04) platelet aggregation and showed a trend toward…

These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.

How this research record was prepared

H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.

Limitations, safety, and original source

Limitations: The reported sample size was small.
The intervention or follow-up period appears relatively short.

Safety: The abstract did not provide detailed safety or adverse-event information.

This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.