Hydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial
Song Guohua, Lin Quanqiang, Zhao Hui, Liu Meiyuan, Ye Fenglong, Sun Yujuan, Yu Yang, Guo Shoudong, Jiao Peng, Wu Yun, Ding Guoyong, Xiao Qiang, Qin Shucun · The Journal of Clinical Endocrinology & Metabolism · 2015
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
The publication “Hydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial” is organized in H2HUBB under the research focus molecular hydrogen mitochondrial function study 2015. The publication is cited as Song Guohua, Lin Quanqiang, Zhao Hui, Liu Meiyuan, Ye Fenglong, Sun Yujuan, Yu Yang, Guo Shoudong, Jiao Peng, Wu Yun, Ding Guoyong, Xiao Qiang, Qin Shucun, The Journal of Clinical Endocrinology & Metabolism, 2015. This randomized controlled trial examined Hydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial. The abstract describes Human participants; sample size 34; reported duration 10 weeks. The abstract reports: H2 activates ATP-binding cassette transporter A1-dependent efflux, enhances HDL antiatherosclerotic functions, and has beneficial lipid-lowering effects. The present findings highlight the potential role of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Molecular hydrogen mitochondrial function study 2015 overview
The purpose of this study was to further characterize the effects of H2-rich water (0.9 L/day) on the content, composition, and biological activities of… Because this is human clinical evidence, relevance depends on participant selection, controls, sample size, treatment duration, adherence, outcome measures, and replication.
Study design and hydrogen intervention
Publication type: Randomized controlled trial. Evidence type: Human clinical evidence. Research model or population: Human participants. Sample size: 34. Randomized: Yes. Blinding: Double-blind. Control status: Placebo-controlled.
Delivery method: Other or not reported. Dose or treatment amount: 0.9 L. Treatment duration: 10 weeks.
Reported findings and scientific interpretation
For this molecular hydrogen mitochondrial function study 2015, the study record reports the following: The abstract reports: H2 activates ATP-binding cassette transporter A1-dependent efflux, enhances HDL antiatherosclerotic functions, and has beneficial lipid-lowering effects. The present findings highlight the potential role of…
These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.
How this research record was prepared
H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.
Limitations, safety, and original source
Limitations: The abstract alone may not report all methodological limitations; full-text review is required.
Safety: The abstract did not provide detailed safety or adverse-event information.
This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.