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Human clinical evidenceHuman Clinical Studyhydrogen-rich water

Pre-Exercise Ingestion of Hydrogen-Rich Cold Water Enhances Endurance Performance and Lactate Response in Heat.

Mariem Khlifi, Nidhal Jebabli, Nejmeddine Ouerghi, Fatma Hilal Yagin, Ashit Kumar Dutta, Reem Alwhaibi, Anissa Bouassida · Medicina (Kaunas, Lithuania) · 2025

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Independent study record

Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

H2HUBB Research Library branded molecular hydrogen research image
Primary topic Molecular Hydrogen Overview
Evidence type Human clinical evidence
Publication type Human Clinical Study
Hydrogen method hydrogen-rich water

H2HUBB TAKEAWAY

In conclusion, findings from this study suggest that ingesting hydrogen-rich cold water effectively mitigates the effects of heat stress, thereby improving endurance performance, enhancing mood, and reducing ratings of perceived exertion.

What the Researchers Studied

The aim of this study was to evaluate the effects of an internal pre-cooling intervention combined with external pre-cooling or hydrogen-rich water on endurance performance in the heat.

How the Study Was Conducted

Double-blind human clinical trial.

How Molecular Hydrogen Was Used

In a double-blind crossover with counterbalanced trials, all participants underwent a shuttle run test after 30 min under the following conditions: (1) hydrogen-rich cold water ingestion (HRCW); (2) cold water ingestion and external pre-cooling (IEPC); and (3) cold-water ingestion (control).

What the Researchers Found

In conclusion, findings from this study suggest that ingesting hydrogen-rich cold water effectively mitigates the effects of heat stress, thereby improving endurance performance, enhancing mood, and reducing ratings of perceived exertion.

Authors’ Conclusion

The authors concluded that in conclusion, findings from this study suggest that ingesting hydrogen-rich cold water effectively mitigates the effects of heat stress, thereby improving endurance performance, enhancing mood, and reducing ratings of perceived exertion.