Hepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice.

This animal study examined Hepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice. The abstract describes Mouse model. The abstract reports: Therefore, the results of this study show that ERW can be proposed to protect the liver against CCl(4)-induced oxidative damage in mice, and the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice.

This animal study examined Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 8 weeks. The abstract reports: Consumption of hydrogen-rich water may be an effective treatment for NASH by reducing hepatic oxidative stress, apoptosis, inflammation, and hepatocarcinogenesis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect of hydrogen-rich water on oxidative stress, liver function, and viral load in patients with chronic hepatitis B.

This uncontrolled human study examined Effect of hydrogen-rich water on oxidative stress, liver function, and viral load in patients with chronic hepatitis B. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: HRW significantly attenuates oxidative stress in CHB patients, but further study with long-term treatment is required to confirm the effect of HRW on liver…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Anti-oxidant and anti-inflammatory effects of hydrogen-rich water alleviate ethanol-induced fatty liver in mice.

This animal study examined Anti-oxidant and anti-inflammatory effects of hydrogen-rich water alleviate ethanol-induced fatty liver in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: HRW protects against chronic EtOH-induced liver injury, possibly by inducing acyl ghrelin to suppress the pro-inflammatory cytokines TNF-α and IL-6 and induce IL-10 and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Electrolyzed Hydrogen Water Protects against Ethanol-Induced Cytotoxicity by Regulating Aldehyde Metabolism-Associated Enzymes in the Hepatic Cell Line HepG2.

This in vitro or cellular study examined Electrolyzed Hydrogen Water Protects against Ethanol-Induced Cytotoxicity by Regulating Aldehyde Metabolism-Associated Enzymes in the Hepatic Cell Line HepG2. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: In this study, we found that EHW inhibits ethanol-induced cytotoxicity by decreasing the intracellular acetaldehyde, a toxic substance produced by ethanol degradation, in hepatocyte…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Long-term consumption of hydrogen-rich water provides hepatoprotection by improving mitochondrial biology and quality control in chronically stressed mice.

This animal study examined Long-term consumption of hydrogen-rich water provides hepatoprotection by improving mitochondrial biology and quality control in chronically stressed mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: This study reveals that long-term hydrogen-rich water (HRW) consumption provides significant hepatoprotection in mice under chronic stress. HRW normalizes liver enzyme levels, enhances antioxidant…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Long-Term Consumption of Hydrogen-Rich Water Mitigates Oxidative Stress, Hepatic Inflammation, and Apoptosis in Rats with LPS-Induced Chronic Liver Injury.

This animal study examined Long-Term Consumption of Hydrogen-Rich Water Mitigates Oxidative Stress, Hepatic Inflammation, and Apoptosis in Rats with LPS-Induced Chronic Liver Injury. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 8 months. This is an automated editorial draft based on the abstract and requires source review before publication.

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A Novel Antioxidant, Hydrogen-Rich Coral Calcium Alters Gut Microbiome and Bile Acid Synthesis to Improve Methionine-and-Choline-Deficient Diet-Induced Non-Alcoholic Fatty Liver Disease.

This animal study examined A Novel Antioxidant, Hydrogen-Rich Coral Calcium Alters Gut Microbiome and Bile Acid Synthesis to Improve Methionine-and-Choline-Deficient Diet-Induced Non-Alcoholic Fatty Liver Disease. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: In the present study, we found that HRCC treatment improved methionine-and-choline-deficient diet (MCD)-induced hepatic steatosis, increased aspartate aminotransferase and alanine aminotransferase levels, and elevated…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Water (HRW) Reduces Fatty Acid-Induced Lipid Accumulation and Oxidative Stress Damage through Activating AMP-Activated Protein Kinase in HepG2 Cells.

This in vitro or cellular study examined Hydrogen-Rich Water (HRW) Reduces Fatty Acid-Induced Lipid Accumulation and Oxidative Stress Damage through Activating AMP-Activated Protein Kinase in HepG2 Cells. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: Some clinical evidence suggests that H may alleviate fatty liver disease, but the precise molecular mechanisms, particularly the regulation of lipid droplet (LD) metabolism,…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Biological Effects of Hydrogen Water on Subjects with NAFLD: A Randomized, Placebo-Controlled Trial.

This randomized controlled trial examined Biological Effects of Hydrogen Water on Subjects with NAFLD: A Randomized, Placebo-Controlled Trial. The abstract describes Human participants; sample size 30; hydrogen delivered as hydrogen water. The abstract reports: The favorable trends in this study in conjunction with previous animal and clinical findings suggest that HRW may serve as an important adjuvant therapy…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water protects against liver injury in nonalcoholic steatohepatitis through HO-1 enhancement via IL-10 and Sirt 1 signaling.

This in vitro or cellular study examined Hydrogen-rich water protects against liver injury in nonalcoholic steatohepatitis through HO-1 enhancement via IL-10 and Sirt 1 signaling. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging.

This animal study examined Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 7 days. The abstract reports: Our findings suggested reduced oxygen utility, mainly in the cortex, in gentamicin-induced nephrotoxicity and an ameliorative effect of hydrogen-rich water against GIN. This is an automated editorial draft based on the abstract and requires source review before publication.

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Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water.

This uncontrolled human study examined Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water. The abstract describes Human participants; reported duration 1 month. The abstract reports: This study demonstrates that hemodialysis with ERW administration may efficiently increase the H2O2- and HOCl-dependent antioxidant defense and reduce H2O2- and HOCl-induced oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.

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Oral hydrogen water prevents chronic allograft nephropathy in rats.

This animal study examined Oral hydrogen water prevents chronic allograft nephropathy in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Rich Water Attenuates Renal Injury and Fibrosis by Regulation Transforming Growth Factor-β Induced Sirt1.

This in vitro or cellular study examined Hydrogen Rich Water Attenuates Renal Injury and Fibrosis by Regulation Transforming Growth Factor-β Induced Sirt1. The abstract describes Epithelial cell model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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