Hydrogen/oxygen therapy for the treatment of an acute exacerbation of chronic obstructive pulmonary disease: results of a multicenter, randomized, double-blind, parallel-group controlled trial

This registered clinical trial examined Hydrogen/oxygen therapy for the treatment of an acute exacerbation of chronic obstructive pulmonary disease: results of a multicenter, randomized, double-blind, parallel-group controlled trial. The abstract describes Planned or registered research population. The abstract reports: The trial demonstrated that hydrogen/oxygen therapy is superior to oxygen therapy in patient with AECOPD with acceptable safety and tolerability profile. This is an automated editorial draft based on the abstract and requires source review before publication.

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Preliminary Effects of Hydrogen-Oxygen Inhalation on Nodule Size, IL-6, and Neutrophils in Patients with Small Pulmonary Nodules

This registered clinical trial examined Preliminary Effects of Hydrogen-Oxygen Inhalation on Nodule Size, IL-6, and Neutrophils in Patients with Small Pulmonary Nodules. The abstract describes Planned or registered research population; sample size 30; hydrogen delivered as oxyhydrogen; reported duration 3 month. The abstract reports: Within the limitations of this single-center, small-sample study with a 3-month follow-up, hydrogen-oxygen inhalation can reduce SPN diameter and downregulate peripheral blood IL-6 and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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A narrative review of hydrogen therapy for COPD: aging-related insights.

This narrative review examined A narrative review of hydrogen therapy for COPD: aging-related insights. The abstract describes Published literature review. The abstract reports: H therapy shows consistent antioxidative, anti-inflammatory, and anti-senescence effects across preclinical and clinical settings, suggesting potential as an adjunctive treatment for COPD in aging…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Can Hydrogen Water Enhance Oxygen Saturation in Patients with Chronic Lung Disease? A Non-Randomized, Observational Pilot Study.

This uncontrolled human study examined Can Hydrogen Water Enhance Oxygen Saturation in Patients with Chronic Lung Disease? A Non-Randomized, Observational Pilot Study. The abstract describes Human participants; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: Treatment with HRW in patients with hypoxia from chronic lung diseases may decrease oxidative stress and improve oxygen saturation in some patients. HRW therapy…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen and radiation protection

This randomized controlled trial examined Molecular hydrogen and radiation protection. The abstract describes Human participants. The abstract reports: A randomised, placebo-controlled investigation also showed consumption of H(2) can improve the quality of life of patients treated with radiotherapy for liver tumours. This is an automated editorial draft based on the abstract and requires source review before publication.

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Randomized double-blind placebo-controlled trial of hydrogen inhalation for Parkinson’s disease: a pilot study

This randomized controlled trial examined Randomized double-blind placebo-controlled trial of hydrogen inhalation for Parkinson’s disease: a pilot study. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: This pilot study revealed that the inhalation of molecular hydrogen gas was safe, but did not show any beneficial effects in patients with PD. This is an automated editorial draft based on the abstract and requires source review before publication.

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A randomized double-blind multi-center trial of hydrogen water for Parkinson’s disease: protocol and baseline characteristics.

This randomized controlled trial examined A randomized double-blind multi-center trial of hydrogen water for Parkinson’s disease: protocol and baseline characteristics. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Our previous randomized double-blind study showed that drinking hydrogen (H2) water for 48 weeks significantly improved the total Unified Parkinson's Disease Rating Scale (UPDRS) score…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Pilot study of H2 therapy in Parkinson’s disease: A randomized double‐blind placebo‐controlled trial

This randomized controlled trial examined Pilot study of H2 therapy in Parkinson’s disease: A randomized double‐blind placebo‐controlled trial. The abstract describes Human participants; sample size 9; reported duration 48 weeks. The abstract reports: The results indicated that drinking H₂-water was safe and well tolerated, and a significant improvement in total UPDRS scores for patients in the H₂-water…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson’s disease.

This randomized controlled trial examined Inhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson’s disease. The abstract describes Human participants; sample size 20; hydrogen delivered as hydrogen water; reported duration 10 minutes. This is an automated editorial draft based on the abstract and requires source review before publication.

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The impact of hydrogen inhalation therapy on blood reactive oxygen species levels: A randomized controlled study

This randomized controlled trial examined The impact of hydrogen inhalation therapy on blood reactive oxygen species levels: A randomized controlled study. The abstract describes Human participants; sample size 37; hydrogen delivered as hydrogen inhalation. The abstract reports: Their results were compared to those of the control group participants who did not undergo HIT. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Beneficial Effects of Hydrogen-Rich Saline Irrigation on Chronic Rhinitis: A Randomized, Double-Blind Clinical Trial.

This randomized controlled trial examined The Beneficial Effects of Hydrogen-Rich Saline Irrigation on Chronic Rhinitis: A Randomized, Double-Blind Clinical Trial. The abstract describes Human participants; sample size 120; hydrogen delivered as hydrogen-rich saline. The abstract reports: Compared to saline irrigation, HRS nasal irrigation was found to improve CR clinical symptoms, especially in patients with AR. HRS could effectively be used…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Effects of 8-Week Hydrogen-Rich Water Consumption on Appetite, Body Composition, Sleep Quality, and Circulating Glucagon-like Peptide-1 in Obese Men and Women (HYDRAPPET): A Randomized Controlled Trial.

This randomized controlled trial examined The Effects of 8-Week Hydrogen-Rich Water Consumption on Appetite, Body Composition, Sleep Quality, and Circulating Glucagon-like Peptide-1 in Obese Men and Women (HYDRAPPET): A Randomized Controlled Trial. The abstract describes Human participants; sample size 36; hydrogen delivered as hydrogen water. The abstract reports: The results demonstrated that hydrogen-rich water significantly mitigated cravings ( = 0.05), improved subjective sleep quality ( = 0.05), reduced total cholesterol ( =…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen affects body composition, metabolic profiles, and mitochondrial function in middle-aged overweight women.

This registered clinical trial examined Molecular hydrogen affects body composition, metabolic profiles, and mitochondrial function in middle-aged overweight women. The abstract describes Planned or registered research population; reported duration 4 week. The abstract reports: It appears that orally administered H as a blend of hydrogen-generating minerals might be a beneficial agent in the management of body composition and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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A randomized controlled double-blind study on the brain protection of infantile patients with epileptic spasm syndrome through atomized inhalation of hydrogen-oxygen gas.

This randomized controlled trial examined A randomized controlled double-blind study on the brain protection of infantile patients with epileptic spasm syndrome through atomized inhalation of hydrogen-oxygen gas. The abstract describes Human participants; hydrogen delivered as oxyhydrogen. The abstract reports: Short-term hydrogen-oxygen nebulization inhalation failed to significantly improve the clinical efficacy of standard treatment for children with IESS. Although it is generally safe and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water and caffeine for alertness and brain metabolism in sleep-deprived habitual coffee drinkers.

This randomized controlled trial examined Hydrogen-rich water and caffeine for alertness and brain metabolism in sleep-deprived habitual coffee drinkers. The abstract describes Human participants; hydrogen delivered as hydrogen water; reported duration 15 min. This is an automated editorial draft based on the abstract and requires source review before publication.

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