Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis.
This uncontrolled human study examined Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. The abstract reports: RESULTS Mice exhibited increases in collagen deposition, hydroxyproline, type I collagen contents, and TGF-β1 production in lung tissues after LPS treatment. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHyperoxygenated Hydrogen-Rich Solution Suppresses Lung Injury Induced by Hemorrhagic Shock in Rats.
This animal study examined Hyperoxygenated Hydrogen-Rich Solution Suppresses Lung Injury Induced by Hemorrhagic Shock in Rats. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: These findings demonstrate that HOHS can protect the lung against ALI induced by hemorrhagic shock. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water ameliorates bronchopulmonary dysplasia (BPD) in newborn rats.
This animal study examined Hydrogen-rich water ameliorates bronchopulmonary dysplasia (BPD) in newborn rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen water alleviates lung injury induced by one-lung ventilation.
This animal study examined Hydrogen water alleviates lung injury induced by one-lung ventilation. The abstract describes Rat model; sample size 32; hydrogen delivered as hydrogen water; reported duration 60 min. The abstract reports: Our data demonstrated that hydrogen water consumption ameliorated OLV-induced lung injury, and it may exert its protective role by its anti-inflammation, antioxidation and reducing…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAttenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats.
This animal study examined Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline pretreatment ameliorated CS-induced airway mucus production and airway epithelium damage in rats. The protective role of hydrogen on CS-exposed rat lungs was…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-enriched water eliminates fine particles from the lungs and blood by enhancing phagocytic activity.
This animal study examined Hydrogen-enriched water eliminates fine particles from the lungs and blood by enhancing phagocytic activity. The abstract describes Mouse model; reported duration 10 weeks. The abstract reports: Collectively, the results indicate that HW not only effectively eliminated PM from the lungs and blood by enhancing phagocytic activity, but also attenuated the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model
This animal study examined Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model. The abstract describes Rat model; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: These results suggest that hydrogen inhalation slows the development of COPD-like lung disease in a cigarette smoke-induced rat model. Higher concentrations of hydrogen may…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice.
This animal study examined Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen gas inhalation improves lung function and protects established airway inflammation in the allergic asthmatic mice model which may be associated with the inhibition…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice.
This uncontrolled human study examined Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice. The abstract describes Human participants; reported duration 8 weeks. The abstract reports: These results demonstrated that H-rich pure water attenuated CS-induced emphysema in SMP30-KO mice by reducing CS-induced oxidative DNA damage and premature cell senescence in…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombination therapy with nitric oxide and molecular hydrogen in a murine model of acute lung injury.
This uncontrolled human study examined Combination therapy with nitric oxide and molecular hydrogen in a murine model of acute lung injury. The abstract describes Human participants. The abstract reports: Moreover, we have found that H2 inhalation can attenuate lung injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen ameliorates endotoxin-induced acute lung injury through AMPK-mediated bidirectional regulation of Caspase3.
This animal study examined Hydrogen ameliorates endotoxin-induced acute lung injury through AMPK-mediated bidirectional regulation of Caspase3. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: The experimental results confirmed that hydrogen provided an essential solution to the dissipative effects of LPS on survival rate, weight loss and lung function. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen in the Treatment of Respiratory Diseases.
Molecular hydrogen is gaining increasing attention as an antioxidant, anti-inflammatory, and antiapoptotic agent. Once considered an inert gas, it reveals current therapeutic potential among others in inflammatory diseases, cancer, and sports medicine, among others. The present review aims to provide a consistent summary of the findings of the last twenty years on the use of molecular hydrogen in major respiratory diseases, including allergies, asthma, COPD, pulmonary fibrosis, lung injury of various origins, as well as cancer and infections of the respiratory tract.
Read MoreCan Hydrogen Water Enhance Oxygen Saturation in Patients with Chronic Lung Disease? A Non-Randomized, Observational Pilot Study.
Recently, chronic lung diseases have been found to be associated with marked inflammation and oxidative stress, which leads to fibrosis in the lungs and chronic respiratory failure. This study aims to determine if hydrogen-rich water (HRW) can enhance oxygen saturation among patients with chronic lung diseases. Ten patients with chronic lung diseases due to COPD ( = 7), bronchial asthma ( = 2), and tuberculosis of the lung ( = 1) with oxygen saturation of 90-95% were provided high-concentration (>5 mM) HRW using H-producing tablets for 4 weeks.
Read MoreHydrogen gas inhalation enhances alveolar macrophage phagocytosis in an ovalbumin-induced asthma model
This animal study examined Hydrogen gas inhalation enhances alveolar macrophage phagocytosis in an ovalbumin-induced asthma model. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Our findings demonstrated that hydrogen gas inhalation enhanced alveolar macrophage phagocytosis in OVA-induced asthmatic mice, which may be associated with the antioxidant effects of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAntioxidant Properties of Hydrogen Gas Attenuates Oxidative Stress in Airway Epithelial Cells.
This in vitro or cellular study examined Antioxidant Properties of Hydrogen Gas Attenuates Oxidative Stress in Airway Epithelial Cells. The abstract describes A549 cell model. The abstract reports: Results show that time-dependent administration of 2% H gas recovered the cells from oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
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