Anti-inflammatory and antitumor action of hydrogen via reactive oxygen species.
Ye Yang, Yaping Zhu, Xiaowei Xi · Oncology letters · 2018
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
This narrative review examined the available molecular-hydrogen literature. Ren et al (50) demonstrated that treatment with 5% H₂-rich water led to a significant decrease in the level of ROS, maintained the biomass and polar growth morphology of the mycelium, and decreased the secondary metabolism under acetic acid -induced oxidative stress ( 50). The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
What the Findings Mean
H2HUBB reviewed this publication as a synthesis of molecular-hydrogen research and summarizes the outcomes emphasized by the authors. Ren et al (50) demonstrated that treatment with 5% H₂-rich water led to a significant decrease in the level of ROS, maintained the biomass and polar growth morphology of the mycelium, and decreased the secondary metabolism under acetic acid -induced oxidative stress ( 50).
What the Researchers Studied
The authors reviewed anti-inflammatory and antitumor action of hydrogen via reactive oxygen species.
What Effects Did Molecular Hydrogen Have?
Source-reported hydrogen concentration: 1% source-reported H₂ gas concentration; Source-reported hydrogen exposure: 1% source-reported H₂ gas concentration. Ren et al (50) demonstrated that treatment with 5% H₂-rich water led to a significant decrease in the level of ROS, maintained the biomass and polar growth morphology of the mycelium, and decreased the secondary metabolism under acetic acid -induced oxidative stress ( 50).
Why These Findings Matter
The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
How Strong Is This Evidence?
This is review or synthesis evidence (narrative review).
Technical Study Details
H2HUBB classifies this publication as narrative review with review or synthesis evidence. The reported sample size was 4. The study used a narrative review. The hydrogen delivery method was hydrogen-rich water. The source-reported hydrogen concentration was 1% source-reported H₂ gas concentration.
Limitations and Safety
No separate limitations or safety findings were identified in the source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base. The original scholarly source is available at https://www.spandidos-publications.com/10.3892/ol.2018.9023/download.