Hydrogen Research Study
← Back to Research Library
Laboratory or cellular evidenceLaboratory StudyOther or not reported

Anti-Oxidative and Anti-Diabetic Effects of Electrolyzed Weakly Alkaline Reduced Water on Renal Proximal Tubular Epithelial Cells

Subham Sharma, Kyu-Jae Lee, Johny Bajgai, Thuy Thi Trinh, Jayson M. Antonio, Md. Habibur Rahman, Kchorng Vira, Abdul-Nasir Sofian, Syung Hyun Cho, Cheol-Su Kim, Yundeok Kim · Processes · 2022

Research-use notice

Independent study record

Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

H2HUBB Research Library branded molecular hydrogen research image
Primary topic Kidney and Renal Health
Evidence type Laboratory or cellular evidence
Publication type Laboratory Study
Hydrogen method Other or not reported

H2HUBB TAKEAWAY

In Electrolyzed weakly alkaline reduced water (EWARW) is known to have anti-oxidative functions in vitro due to its bioactive properties, here, HK-2 cells were treated with 71.68 mM glucose to induce OS and then treated with 10% tap water (TW)_7.7, electrolyzed alkaline reduced water (EARW)_9.5, or EARW_8.5 for 24 h. These findings from a laboratory model add evidence supporting molecular hydrogen's biological and therapeutic potential in the model studied.

What the Findings Mean

H2HUBB reviewed how molecular hydrogen affected the outcomes measured in Electrolyzed weakly alkaline reduced water (EWARW) is known to have anti-oxidative functions in vitro due to its bioactive properties. Here, HK-2 cells were treated with 71.68 mM glucose to induce OS and then treated with 10% tap water (TW)_7.7, electrolyzed alkaline reduced water (EARW)_9.5, or EARW_8.5 for 24 h.

What the Researchers Studied

The researchers studied Electrolyzed weakly alkaline reduced water (EWARW) is known to have anti-oxidative functions in vitro due to its bioactive properties. The study used a in vitro cell-culture laboratory experiment.

What Effects Did Molecular Hydrogen Have?

Here, HK-2 cells were treated with 71.68 mM glucose to induce OS and then treated with 10% tap water (TW)_7.7, electrolyzed alkaline reduced water (EARW)_9.5, or EARW_8.5 for 24 h.

Why These Findings Matter

These findings from a laboratory model add evidence supporting molecular hydrogen's biological and therapeutic potential in the model studied.

How Strong Is This Evidence?

This is laboratory evidence from a in vitro cell-culture laboratory experiment. It is most informative for the biological mechanisms, cellular responses, or biochemical outcomes directly measured.

Technical Study Details

H2HUBB classifies this publication as laboratory study with laboratory or cellular evidence. The research population or model was Electrolyzed weakly alkaline reduced water (EWARW) is known to have anti-oxidative functions in vitro due to its bioactive properties. The study used a in vitro cell-culture laboratory experiment.

Limitations and Safety

No separate limitations or safety findings were identified in the current-study source text available to H2HUBB.

Original Study and H2HUBB Research Context

H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base. The original scholarly source is available at https://www.mdpi.com/2227-9717/10/10/2025/pdf.