Determination of rifaximin treatment period according to lactulose breath test values in nonconstipated irritable bowel syndrome subjects.
Suhyun Bae, Kwang Jae Lee, Young-Sang Kim, Kyu-Nam Kim · Journal of Korean medical science · 2015
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
This narrative review examined the available molecular-hydrogen literature. A post hoc analysis between the treatment period for the 4 weeks group and the 12 weeks groups were statistically significant in terms of the H₂ value at 90 min and its sum during 90 min. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
What the Findings Mean
H2HUBB reviewed this publication as a synthesis of molecular-hydrogen research and summarizes the outcomes emphasized by the authors. A post hoc analysis between the treatment period for the 4 weeks group and the 12 weeks groups were statistically significant in terms of the H₂ value at 90 min and its sum during 90 min.
What the Researchers Studied
The authors reviewed determination of rifaximin treatment period according to lactulose breath test values in nonconstipated irritable bowel syndrome subjects.
What Effects Did Molecular Hydrogen Have?
Reported treatment duration: 4 weeks. A post hoc analysis between the treatment period for the 4 weeks group and the 12 weeks groups were statistically significant in terms of the H₂ value at 90 min and its sum during 90 min. The authors concluded that the results indicate that different rifaximin treatment periods are needed in accordance with LBT levels to effectively eradicate SIBO.
Why These Findings Matter
The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
How Strong Is This Evidence?
This is review or synthesis evidence (narrative review).
Technical Study Details
H2HUBB classifies this publication as narrative review with review or synthesis evidence. The reported sample size was 102. The study used a narrative review. The reported treatment duration was 4 weeks.
Limitations and Safety
Reported limitations: A further limitation of the study is related to the ongoing controversy regarding the validity and interpretation of the LBT in SIBO.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.