Different effects of hydrogen-rich water intake and hydrogen gas inhalation on gut microbiome and plasma metabolites of rats in health status.
Fei Xie, Xue Jiang, Yang Yi, Zi-Jia Liu, Chen Ma, Jin He, Zhi-Ming Xun, Meng Wang, Meng-Yu Liu, Yao Mawulikplimi Adzavon, Peng-Xiang Zhao, Xue-Mei Ma · Scientific reports · 2022
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Independent study record
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H2HUBB TAKEAWAY
In rats, the metabolic function was determined by metabolic cage analysis and showed that HI decreased the voluntary intake and excretions of rats, while HRW intake did not. These results are preclinical and add to understanding of how molecular hydrogen affects the condition studied. Further human research is needed to determine its clinical relevance.
What the Researchers Studied
Rats
How Molecular Hydrogen Was Used
The potential for preventive and therapeutic applications of H₂ have now been confirmed in various disease. However, the effects of H₂ on health status have not been fully elucidated. The authors' previous study reported changes in the body weight and 13 serum biochemical parameters during the six-month hydrogen intervention.
What the Researchers Found
The metabolic function was determined by metabolic cage analysis and showed that HI decreased the voluntary intake and excretions of rats, while HRW intake did not.
Biological or Mechanistic Findings
Determination of the effects of hydrogen intervention on microbiota profiles could also shed light on identification of mechanism underlying the biological effects of molecular hydrogen.
Authors’ Conclusion
These results are preclinical and add to understanding of how molecular hydrogen affects the condition studied. Further human research is needed to determine its clinical relevance.