Early Hydrogen-Oxygen Gas Mixture Inhalation in Patients with Aneurysmal Subarachnoid Hemorrhage (HOMA): study protocol for a randomized controlled trial.
Fa Lin, Runting Li, Yu Chen, Jun Yang, Ke Wang, Yitong Jia, Heze Han, Qiang Hao, Guangzhi Shi, Shuo Wang, Yuanli Zhao, Xiaolin Chen · Trials · 2024
Research-use notice
Independent study record
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H2HUBB TAKEAWAY
This publication examined hydrogen gas using the study design reported by the authoritative source. No study results are reported because this publication is a protocol.
What the Study Plans to Test
The diversity of hydrogen therapeutic targets has been largely reported in basic research, unveiling its latent capacity to ameliorate EBI in aSAH patients.
Planned Hydrogen Intervention
A cohort of 206 patients will be randomized to either hydrogen-oxygen gas mixture inhalation group (8 h per day, 3 L/min, hydrogen concentration of 67%, oxygen concentration of 33%) or oxygen inhalation group (8 h per day, 3 L/min, oxygen concentration of 33%) within 72 h after aSAH and treated for 7 days in the ICU ward.
Current Study Status
This publication describes a planned or ongoing study; H2HUBB presents it as a protocol rather than as completed outcome evidence.