Hydrogen Research Study
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Human clinical evidenceHuman Clinical StudyOther or not reported

Effects of Hydrogen-Infused Water on Endurance Performance, Body Hydration Biomarkers, and Health-Related Quality of Life in Collegiate Athletes (HYDRO2EAU): A Randomized-Controlled Clinical Trial

Kuzmanović J, Todorovic N, Ranisavljev M, Nedeljkovic D, Ostojic SM · 2025

Research-use notice

Independent study record

Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

H2HUBB Research Library branded molecular hydrogen research image
Primary topic Exercise, Athletics, and Recovery
Evidence type Human clinical evidence
Publication type Human Clinical Study
Hydrogen method Other or not reported

H2HUBB TAKEAWAY

The findings indicate that HIW is a safe and potentially effective intervention for enhancing both physical performance and overall well-being in active individuals. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.

What the Findings Mean

H2HUBB reviewed how molecular hydrogen was evaluated in this publication and summarizes the source-grounded findings below. The findings indicate that HIW is a safe and potentially effective intervention for enhancing both physical performance and overall well-being in active individuals.

What the Researchers Studied

The study used a randomized, double-blind, placebo-controlled, crossover human clinical trial. The comparison condition was placebo.

What Effects Did Molecular Hydrogen Have?

Consumed 660 mL daily of either HIW (300 μmol/L dihydrogen) or control water (0 μmol/L dihydrogen) for four weeks, with a two-week washout period between interventions. The findings indicate that HIW is a safe and potentially effective intervention for enhancing both physical performance and overall well-being in active individuals.

Why These Findings Matter

These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study and contribute to the growing body of molecular-hydrogen research.

How Strong Is This Evidence?

This is human clinical evidence from a randomized, double-blind, placebo-controlled, crossover human clinical trial. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.

Technical Study Details

H2HUBB classifies this publication as human clinical study with human clinical evidence. The reported sample size was 6. The study used a randomized, double-blind, placebo-controlled, crossover human clinical trial.

Limitations and Safety

No separate limitations or safety findings were identified in the current-study source text available to H2HUBB.

Original Study and H2HUBB Research Context

H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base. The original scholarly source is available at https://europepmc.org/article/PPR/PPR1014162.