Effects of hydrogen-rich water on abnormalities in a SHR.Cg-Leprcp/NDmcr rat – a metabolic syndrome rat model.
Michio Hashimoto, Masanori Katakura, Toru Nabika, Yoko Tanabe, Shahdat Hossain, Satoru Tsuchikura, Osamu Shido · Medical gas research · 2011
Research-use notice
Independent study record
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H2HUBB TAKEAWAY
The urinary ratio of albumin to creatinine was significantly lower and creatinine clearance was higher in the HRW group than in the control group. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
What the Researchers Studied
The researchers investigated whether hydrogen-rich water (HRW) affects metabolic abnormalities in the metabolic syndrome rat model, SHR.Cg-Leprcp/NDmcr (SHR-cp).
How Molecular Hydrogen Was Used
Molecular hydrogen was administered as hydrogen-rich water.
What the Researchers Found
The urinary ratio of albumin to creatinine was significantly lower and creatinine clearance was higher in the HRW group than in the control group.
H₂ Mechanisms / Biological Findings
The source material reviewed did not establish a specific molecular hydrogen mechanism for the reported findings.
Authors’ Conclusion
The authors concluded that the present findings suggest that HRW conferred significant benefits against abnormalities in the metabolic syndrome model rats, at least by preventing and ameliorating glomerulosclerosis and creatinine clearance.