Hydrogen Research Study
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Human clinical evidenceHuman Clinical Studyhydrogen-rich water

Electrolyzed hydrogen-rich water for oxidative stress suppression and improvement of insulin resistance: a multicenter prospective double-blind randomized control trial.

Susumu Ogawa, Yusuke Ohsaki, Manami Shimizu, Kazuhiro Nako, Masashi Okamura, Shigeru Kabayama, Kiyoshi Tabata, Yasuhisa Tanaka, Sadayoshi Ito · Diabetology international · 2022

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Independent study record

Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

H2HUBB Research Library branded molecular hydrogen research image
Primary topic Molecular Hydrogen Overview
Evidence type Human clinical evidence
Publication type Human Clinical Study
Hydrogen method hydrogen-rich water

H2HUBB TAKEAWAY

In 50 patients with T2DM, however, lactate levels decreased significantly in the EHW group, and this decrease was significantly correlated with a reduction in HOMA-IR, fasting plasma glucose, and fasting plasma insulin level.

What the Researchers Studied

50 patients with T2DM.

How the Study Was Conducted

Randomized, double-blind human clinical trial.

How Molecular Hydrogen Was Used

Hydrogen-rich water

What the Researchers Found

However, lactate levels decreased significantly in the EHW group, and this decrease was significantly correlated with a reduction in HOMA-IR, fasting plasma glucose, and fasting plasma insulin level.

Authors’ Conclusion

The authors concluded that there were no significant effect of EHW in the change in HOMA-IR in this study; larger-scale and longer-term study are needed to verify the effects of EHW in T2DM patients.