Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage.
S Shirahata, S Kabayama, M Nakano, T Miura, K Kusumoto, M Gotoh, H Hayashi, K Otsubo, S Morisawa, Y Katakura · Biochemical and biophysical research communications · 1997
Research-use notice
Independent study record
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H2HUBB TAKEAWAY
Water bubbled with hydrogen gas exhibited low DO, extremely high DH and extremely low RP values, as does reduced water, but it has no SOD-like activity. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
What the Publication Examined
Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage.
How Molecular Hydrogen Was Addressed
The ideal scavenger for active oxygen should be 'active hydrogen'. can be produced in reduced water near the cathode during electrolysis of water. Reduced water exhibits high pH, low dissolved oxygen (DO), extremely high dissolved molecular hydrogen (DH), and extremely negative redox potential (RP) values. The superoxide dismutase (SOD)-like activity of reduced water is stable at 4 degrees C for over a month and was not lost even after neutralization, repeated freezing and melting, deflation with sonication, vigorous mixing, boiling, repeated filtration, or closed autoclaving. But was lost by opened autoclaving or by closed autoclaving in the presence of tungsten trioxide which efficiently adsorbs active atomic hydrogen.
What the Publication Reported
Water bubbled with hydrogen gas exhibited low DO, extremely high DH and extremely low RP values, as does reduced water, but it has no SOD-like activity.
Authors’ Conclusion
The authors concluded that reduce water suppresses single-strand breakage of DNA b active oxygen species produced by the Cu(II)-catalyzed oxidation of ascorbic acid in a dose-dependent manner, suggesting that reduced water can scavenge not only O₂.- and H₂O₂, but also 1O2 and.OH.