Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch.
Yinghao Niu, Qingrong Nie, Liping Dong, Jihua Zhang, Shu Fang Liu, Wei Song, Xiaopei Wang, Guangli Wu, Dongmei Song · Scientific reports · 2020
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In Activities of glycolytic and mitochondrial oxidative phosphorylation systems were assessed in asthmatic patients and in mouse model of allergic airway inflammation, treatment of ovalbumin-sensitized and challenged mice with hydrogen reversed the energy metabolic pathway switch, and mitigated airway inflammation.
What the Researchers Studied
Activities of glycolytic and mitochondrial oxidative phosphorylation systems were assessed in asthmatic patients and in mouse model of allergic airway inflammation.
How the Study Was Conducted
Human clinical study
What the Researchers Found
Treatment of ovalbumin-sensitized and challenged mice with hydrogen reversed the energy metabolic pathway switch, and mitigated airway inflammation.