Hydrogen molecules (H2) improve perfusion recovery via antioxidant effects in experimental peripheral arterial disease.
Jinrong Fu, Jinjing Zou, Cheng Chen, Hongying Li, Lei Wang, Yanli Zhou · Molecular medicine reports · 2018
Research-use notice
Independent study record
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H2HUBB TAKEAWAY
In a laboratory model, laser Doppler perfusion imaging demonstrated that H₂‐saturated water improved perfusion recovery, decreased the rate of necrosis, increased the capillary density in the gastrocnemius muscle and increased the artery density in the abductor muscle in the ischemic limbs, at 14 and 21 days post‐hindlimb ischemia. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to determine clinical relevance.
What the Researchers Tested
Laboratory experiment
What Molecular Hydrogen Changed
Laser Doppler perfusion imaging demonstrated that H₂‐saturated water improved perfusion recovery, decreased the rate of necrosis, increased the capillary density in the gastrocnemius muscle and increased the artery density in the abductor muscle in the ischemic limbs, at 14 and 21 days post‐hindlimb ischemia.
Authors’ Conclusion
These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to determine clinical relevance.