Hydrogen-Rich Saline as an Innovative Therapy for Cataract: A Hypothesis.
Limin Qin, Ye Tao, Liqiang Wang, Hong Chen, Ying Liu, Yi Fei Huang · Medical science monitor : international medical journal of experimental and clinical research · 2016
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
Increasing evidence indicates that oxidative stress is an important risk factor contributing to the development of cataract. This publication is a scientific hypothesis or perspective about molecular hydrogen and identifies directions for further research.
What the Publication Proposes
Increasing evidence indicates that oxidative stress is an important risk factor contributing to the development of cataract.
Evidence Supporting the Idea
Molecular hydrogen has recently been verified to have protective and therapeutic value as an antioxidant through its ability to selectively reduce cytotoxic ROS such as hydroxyl radical (OH). Hitherto, hydrogen has been used as a therapeutic element against multiple pathologies in both animal models and human patients. Unlike most well-known antioxidants, which are unable to successfully target organelles, hydrogen has advantageous distribution characteristics enabling it to penetrate biomembranes and diffuse into the cytosol, mitochondria, and nucleus. Consequently, the researchers speculate that hydrogen might be an effective antioxidant to protect against lens damage, and it is important to further explore the biological mechanism underlying its potential therapeutic effects.
H₂ Mechanisms / Biological Findings
Consequently, the researchers speculate that hydrogen might be an effective antioxidant to protect against lens damage, and it is important to further explore the biological mechanism underlying its potential therapeutic effects.
Authors’ Conclusion
The authors concluded that increasing evidence indicates that oxidative stress is an important risk factor contributing to the development of cataract.