Hydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life.
Kei Mizuno, Akihiro T Sasaki, Kyoko Ebisu, Kanako Tajima, Osami Kajimoto, Junzo Nojima, Hirohiko Kuratsune, Hiroshi Hori, Yasuyoshi Watanabe · Medical gas research · 2017
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In 26 participants with a two-way crossover design, these results suggest that HRW may reinforce QOL through effects that increase central nervous system functions involving mood, anxiety, and autonomic nerve function. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
What the Findings Mean
H2HUBB reviewed how hydrogen-rich water affected the outcomes measured in 26 participants with a two-way crossover design. These results suggest that HRW may reinforce QOL through effects that increase central nervous system functions involving mood, anxiety, and autonomic nerve function.
What the Researchers Studied
The researchers studied 26 participants with a two-way crossover design. The study used a randomized, double-blind, placebo-controlled, crossover human clinical trial. The comparison condition was placebo.
What Effects Did Molecular Hydrogen Have?
600 mL hydrogen-rich water per reported dose; dissolved H₂ concentration was not reported in the available source text, so H2HUBB did not estimate milligrams of H₂; reported treatment duration: 4 weeks. These results suggest that HRW may reinforce QOL through effects that increase central nervous system functions involving mood, anxiety, and autonomic nerve function.
Why These Findings Matter
These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study and contribute to the growing body of molecular-hydrogen research.
How Strong Is This Evidence?
This is human clinical evidence from a randomized, double-blind, placebo-controlled, crossover human clinical trial. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.
Technical Study Details
H2HUBB classifies this publication as human clinical study with human clinical evidence. The research population or model was 26 participants with a two-way crossover design. The reported sample size was 26. The study used a randomized, double-blind, placebo-controlled, crossover human clinical trial. The hydrogen delivery method was hydrogen-rich water. H2HUBB translates the reported hydrogen dose as 600 mL hydrogen-rich water per reported dose; dissolved H₂ concentration was not reported in the available source text, so H2HUBB did not estimate milligrams of H₂. The reported treatment duration was 4 weeks.
Limitations and Safety
No separate limitations or safety findings were identified in the source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.