Effect of hydrogen-rich water on the lactic acid level in metformin-treated diabetic rats under hypoxia.
Zhao C, Guo Y, Wang R, Cheng C, Chen X · The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2021
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Independent study record
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The publication “Effect of hydrogen-rich water on the lactic acid level in metformin-treated diabetic rats under hypoxia.” is organized in H2HUBB under the research focus hydrogen water diabetes metabolic study 2021. The publication is cited as Zhao C, Guo Y, Wang R, Cheng C, Chen X, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2021. This uncontrolled human study examined Effect of hydrogen-rich water on the lactic acid level in metformin-treated diabetic rats under hypoxia. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: We found that the levels of lactic acid, pyruvate and lactate dehydrogenase were significantly lower in the blood of DMMHR group than DMMH group. This is an automated editorial draft based on the abstract and requires source review before publication.
Hydrogen water diabetes metabolic study 2021 overview
The present study aims to investigate the impact of hydrogen-rich water on the lactic acid level in metformin-treated diabetic rats under hypoxia. Because this is human clinical evidence, relevance depends on participant selection, controls, sample size, treatment duration, adherence, outcome measures, and replication.
Study design and hydrogen intervention
Publication type: Uncontrolled human study. Evidence type: Human clinical evidence. Research model or population: Human participants. Blinding: Unknown. Control status: Unknown.
Delivery method: Hydrogen water.
Reported findings and scientific interpretation
For this hydrogen water diabetes metabolic study 2021, the study record reports the following: The abstract reports: We found that the levels of lactic acid, pyruvate and lactate dehydrogenase were significantly lower in the blood of DMMHR group than DMMH group.
These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.
How this research record was prepared
H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.
Limitations, safety, and original source
Limitations: The abstract alone may not report all methodological limitations; full-text review is required.
Safety: The abstract did not provide detailed safety or adverse-event information.
This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.