Hydrogen Research Study
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Human clinical evidenceHuman Clinical Studyhydrogen-rich water

Hydrotherapy with hydrogen-rich water compared with RICE protocol following acute ankle sprain in professional athletes: a randomized non-inferiority pilot trial.

Dejan Javorac, Valdemar Stajer, Laszlo Ratgeber, Andras Olah, Jozsef Betlehem, Pongras Acs, Boris Vukomanovic, Sergej M Ostojic · Research in sports medicine (Print) · 2021

Research-use notice

Independent study record

Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

H2HUBB Research Library branded molecular hydrogen research image
Primary topic Exercise, Athletics, and Recovery
Evidence type Human clinical evidence
Publication type Human Clinical Study
Hydrogen method hydrogen-rich water

How Molecular Hydrogen Was Used

Hydrogen group received six 30-min ankle baths with HRW throughout the first 24 h post-injury, with hydrotherapy administered every 4 hours during the intervention period.

What the Researchers Found

Professional athletes (age 23.7 ± 4.0 years; weight 78.6 ± 5.7 kg, height 182.5 ± 4.3 cm; professional experience 5.9 ± 3.9 years) who incurred AAS during a sport-related activity were randomly assigned immediately after the injury to either hydrogen group (n = 9) or a conventional RICE treatment group (n = 9). Hydrogen group received six 30-min ankle baths with HRW throughout the first 24 h post-injury, with hydrotherapy administered every 4 hours during the intervention period.

H₂ Mechanisms / Biological Findings

The source material reviewed did not establish a specific molecular hydrogen mechanism for the reported findings.

Authors’ Conclusion

A distinct authors’ conclusion was not available in the source material reviewed by H2HUBB.

H2HUBB TAKEAWAY

This pilot study suggests therapeutic potential, while larger randomized, placebo-controlled studies are needed to confirm the finding.

What the Researchers Studied

The study examined the researchers analysed the effects of an experimental novel protocol of intensive hydrotherapy with hydrogen-rich water (HRW) on injury recovery in athletic men who suffered an acute ankle sprain (A.