In situ-built chemo-electroactive hydrogel incorporating Mg-based hydrogen generators for osteoarthritis therapy.
Hongyu Zhong, Qi He, Fang Qin, Yao Shu, Yijian Wang, Xiang Yang, Zhonghao Chen, Sheng Yao, Chuxuan Gui, Jing Xiang, Lu Liu, Yun Chen, Yingfeng Tu, Kun Liu, Jinghui Yao · Materials today. Bio · 2026
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Independent study record
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The study reports that 4 We innovatively developed the microenvironment-responsive, chemo-electroactive PHO-MHG@BP hydrogel with favorable injectability and self-healing capability.
What the Researchers Studied
Source-reported study description: 2.1 Magnesium powder was purchased from Tangshan Weihao Magnesium Powder Co., Ltd., and black phosphorus crystal powder was obtained from Sichuan KaqiKun Technology.
Source-reported study description: Fresh Tibetan mini pig skin was provided by Guangzhou Huateng Biotechnology (License No.
What the Study Found
The authors reported: Statistical analysis was performed using one-way ANOVA followed by Tukey's post-hoc multiple comparison test (* p < 0.05, ** p < 0.01, and *** p < 0.001). (For interpretation of the references to color in this figure legend, the reader is referred…
The authors reported: Relative to the Blank group, the PHO-MHG@BP group exhibited a marked restoration in the gene expression levels of Col2 , Aggrecan , and SOX9 (*p < 0.001), accompanied by the effective suppression of MMP13 and ADAMTS5 (*p < 0.001).
What the Findings Mean
The authors concluded/reported: 4 We innovatively developed the microenvironment-responsive, chemo-electroactive PHO-MHG@BP hydrogel with favorable injectability and self-healing capability.
Study Details
Publication type: other_research
Evidence source level: A_FULL_TEXT
Original scholarly source: https://pmc.ncbi.nlm.nih.gov/articles/PMC13553581/