Measurement of cutaneous blood flow by clearance of hydrogen gas generated by electrolysis.
S Suzuki, N Isshiki, Y Ogawa, M Ohtsuka, K Nose, R Nishimura · Annals of plastic surgery · 1985
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
The results showed high accuracy in obtained values, good reproducibility in the repeated measurements, and consistency with the values obtained by the hydrogen gas inhalation method. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
What the Findings Mean
H2HUBB reviewed how molecular hydrogen affected the outcomes measured in rats. The results showed high accuracy in obtained values, good reproducibility in the repeated measurements, and consistency with the values obtained by the hydrogen gas inhalation method.
What the Researchers Studied
The researchers studied rats. The study used a preclinical animal experiment.
What Effects Did Molecular Hydrogen Have?
In an attempt to assess the reliability of a method for measurement of local blood flow—namely, the clearance of electrochemically generated hydrogen gas—a series of experiments were conducted using the skin and skin flap in rats and rabbits. The results showed high accuracy in obtained values, good reproducibility in the repeated measurements, and consistency with the values obtained by the hydrogen gas inhalation method. The authors concluded that the present study suggests a wide potential application of this method in plastic surgery because of its high reliability and because no radioactivity is involved.
Why These Findings Matter
These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
How Strong Is This Evidence?
This is preclinical animal evidence from a preclinical animal experiment. It is most informative for the disease model, mechanisms, biomarkers, and outcomes directly measured in the study.
Technical Study Details
H2HUBB classifies this publication as animal study with preclinical animal evidence. The research population or model was rats. The study used a preclinical animal experiment.
Limitations and Safety
No separate limitations or safety findings were identified in the current-study source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base. The original scholarly source is available at https://www.ovid.com/jnls/annalsplasticsurgery/abstract/00000637-198509000-00001~measurement-of-cutaneous-blood-flow-by-clearance-of-hydrogen?redirectionsource=fulltextview.