Hydrogen Research Study
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Human clinical evidenceHuman Clinical StudyOther or not reported

The Effect of Electrolyzed Hydrogen-Rich Alkaline Reduced Water on Patients with Chronic Constipation—A Clinical Trial

Subham Sharma, Yundeok Kim, Johny Bajgai, Md. Habibur Rahman, Yun Ju Jeong, Seong Hoon Goh, Hong Jun Park, Cheol-Su Kim, Hyun Il Kim, Kyu-Jae Lee · Processes · 2023

Research-use notice

Independent study record

Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

H2HUBB Research Library branded molecular hydrogen research image
Primary topic Molecular Hydrogen Overview
Evidence type Human clinical evidence
Publication type Human Clinical Study
Hydrogen method Other or not reported

H2HUBB TAKEAWAY

In 5 patients with chronic constipation were enrolled after screening as intention-to-treat (ITT), electrolyzed hydrogen-rich alkaline reduced water (EHARW) helps treat gastrointestinal disorders owing to its various bioactive properties. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.

What the Findings Mean

H2HUBB reviewed how molecular hydrogen affected the outcomes measured in 5 patients with chronic constipation were enrolled after screening as intention-to-treat (ITT). Electrolyzed hydrogen-rich alkaline reduced water (EHARW) helps treat gastrointestinal disorders owing to its various bioactive properties.

What the Researchers Studied

The researchers studied 5 patients with chronic constipation were enrolled after screening as intention-to-treat (ITT). The study used a human clinical study.

What Effects Did Molecular Hydrogen Have?

The selected patients were instructed to drink EHARW (pH 9.5; H₂ ≈ 0.5 mg/L) (20 mL/kg body weight/day) generated from a home medical device for four weeks. Electrolyzed hydrogen-rich alkaline reduced water (EHARW) helps treat gastrointestinal disorders owing to its various bioactive properties.

Why These Findings Matter

These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study and contribute to the growing body of molecular-hydrogen research.

How Strong Is This Evidence?

This is human clinical evidence from a human clinical study. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.

Technical Study Details

H2HUBB classifies this publication as human clinical study with human clinical evidence. The research population or model was 5 patients with chronic constipation were enrolled after screening as intention-to-treat (ITT). The reported sample size was 2. The study used a human clinical study.

Limitations and Safety

No separate limitations or safety findings were identified in the source text available to H2HUBB.

Original Study and H2HUBB Research Context

H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base. The original scholarly source is available at https://www.mdpi.com/2227-9717/11/7/2142/pdf.