Protective effect of hydrogen-rich medium against high glucose-induced apoptosis of Schwann cells in vitro.
Yu Y, Ma X, Yang T, Li B, Xie K, Liu D, Wang G, Yu Y · Molecular medicine reports · 2015
Research-use notice
Independent study record
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The publication “Protective effect of hydrogen-rich medium against high glucose-induced apoptosis of Schwann cells in vitro.” is organized in H2HUBB under the research focus molecular hydrogen diabetes metabolic study 2015. The publication is cited as Yu Y, Ma X, Yang T, Li B, Xie K, Liu D, Wang G, Yu Y, Molecular medicine reports, 2015. This uncontrolled human study examined Protective effect of hydrogen-rich medium against high glucose-induced apoptosis of Schwann cells in vitro. The abstract describes Human participants. The abstract reports: HG was found to induce severe oxidative stress and promote the caspase‑dependent and caspase‑independent apoptosis of SCs. This is an automated editorial draft based on the abstract and requires source review before publication.
Molecular hydrogen diabetes metabolic study 2015 overview
The aim of the present study was to investigate the protective effects of hydrogen‑rich medium (HM) on high glucose (HG)‑mediated oxidative stress, PARP‑1 activation… Laboratory and cellular research can clarify mechanisms, but it does not establish clinical benefit or reproduce the complexity of a living human system.
Study design and hydrogen intervention
Publication type: In vitro or cellular study. Evidence type: Laboratory or cellular evidence. Research model or population: Schwann cell culture. Blinding: Unknown. Control status: Unknown.
Delivery method: Other or not reported.
Reported findings and scientific interpretation
For this molecular hydrogen diabetes metabolic study 2015, the study record reports the following: The abstract reports: HG was found to induce severe oxidative stress and promote the caspase‑dependent and caspase‑independent apoptosis of SCs.
These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.
How this research record was prepared
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Limitations, safety, and original source
Limitations: The abstract alone may not report all methodological limitations; full-text review is required.
Safety: The abstract did not provide detailed safety or adverse-event information.
This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.