Evaluation of the safety and potential lipid-lowering effects of oral hydrogen-rich coral calcium (HRCC) capsules in patients with metabolic syndrome: a prospective case series study.
Szu-Han Chiu, Frank L Douglas, Jia-Ru Chung, Kuang-Yih Wang, Chao-Fang Chu, Hsia-Yun Chou, Wei-Chih Huang, Tian-Yu Wang, Wen-Wen Chen, Min-Chung Shen, Feng-Cheng Liu, Po-Jen Hsiao · Frontiers in nutrition · 2023
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
These findings add human evidence that helps define the outcomes that did and did not change with molecular hydrogen in this study.
What the Findings Mean
QOL showed no significant changes.
What the Researchers Studied
The comparison condition was control condition or baseline measurements.
What Effects Did Molecular Hydrogen Have?
Hydrogen capsules (PURE HYDROGEN) were purchased from HoHo Biotech Co., Ltd. (Taipei, Taiwan). QOL showed no significant changes. The authors concluded that this study is the first human clinical trial evaluating HRCC capsules in patients with metabolic syndrome. While the detailed mechanism is not well known, the significant decrease in TG could help explain the findings regarding the role of hydrogen in mediating TG by reducing excess oxidative stress.
Why These Findings Matter
This publication adds useful evidence about where molecular hydrogen did and did not change the measured outcomes, helping define the larger therapeutic evidence base.
How Strong Is This Evidence?
This is human clinical evidence from a case report. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.
Technical Study Details
H2HUBB classifies this publication as case report with human clinical evidence. The hydrogen delivery method was inhaled hydrogen gas.
Limitations and Safety
No separate limitations or safety findings were identified in the source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.