Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water.
Kuo-Chin Huang, Chih-Ching Yang, Kun-Tai Lee, Chiang-Ting Chien · Kidney international · 2003
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
Hemodialysis reduced the plasma ROS scavenging activity, as shown by the augmented reference H₂O₂ and HOCl counts (Rh2o2 and Rhocl, respectively) and decreased antioxidative activity (expressed as total antioxidant status in this study). This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
What the Publication Examined
Electrolyzed reduced water (ERW) with reactive oxygen species (ROS) scavenging ability may have a potential effect on reduction of hemodialysis-induced oxidative stress in ESRD patients.
What the Publication Reported
Hemodialysis reduced the plasma ROS scavenging activity, as shown by the augmented reference H₂O₂ and HOCl counts (Rh2o2 and Rhocl, respectively) and decreased antioxidative activity (expressed as total antioxidant status in this study).
Authors’ Conclusion
The authors concluded that this study demonstrates that hemodialysis with ERW administration may efficiently increase the H₂O₂- and HOCl-dependent antioxidant defense and reduce H₂O₂- and HOCl-induced oxidative stress.