ONOOH does not react with H2: Potential beneficial effects of H2 as an antioxidant by selective reaction with hydroxyl radicals and peroxynitrite.
Jelle Penders, Reinhard Kissner, Willem H Koppenol · Free radical biology & medicine · 2014
Research-use notice
Independent study record
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H2HUBB TAKEAWAY
The study reports that The reaction of H2 with HO(⋅) has been studied by pulse radiolysis in the past and is too slow to be physiologically relevant, not to mention that the…
What the Researchers Studied
Source-reported study description: H2 has been suggested to act as an antioxidant when administered just before the reperfusion phase of induced oxidative stress.
Source-reported study description: These effects have been reported, for example, for the heart, brain, and liver.
What the Study Found
The authors reported: It is hypothesized that this beneficial effect may be due to selective scavenging of HO(⋅) and ONOOH by H2.
What the Findings Mean
The authors concluded/reported: The reaction of H2 with HO(⋅) has been studied by pulse radiolysis in the past and is too slow to be physiologically relevant, not to mention that the…
Study Details
Publication type: other_research
Evidence source level: B_ABSTRACT
Original scholarly source: https://pubmed.ncbi.nlm.nih.gov/25086438/