Potential application of hydrogen in traumatic and surgical brain injury, stroke and neonatal hypoxia-ischemia.
Jan M Eckermann, Paul R Krafft, Lorelei Shoemaker, Robert E Lieberson, Steven D Chang, Austin Colohan · Medical gas research · 2012
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
Most reviewed studies demonstrated neuroprotective effects of hydrogen administration. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
How Molecular Hydrogen Was Addressed
This article summarized findings of current preclinical studies that implemented hydrogen administration, either in the gas or liquid form, as treatment application for neurological disorders including traumatic brain injury (TBI), surgically induced brain injury (SBI), stroke, and neonatal hypoxic-ischemic brain insult (HI). Most reviewed studies demonstrated neuroprotective effects of hydrogen administration. Even though anti-oxidative potentials have been reported in several studies, further neuroprotective mechanisms of hydrogen therapy remain to be elucidated.
What the Publication Reported
Most reviewed studies demonstrated neuroprotective effects of hydrogen administration.
H₂ Mechanisms / Biological Findings
Even though anti-oxidative potentials have been reported in several studies, further neuroprotective mechanisms of hydrogen therapy remain to be elucidated.