The effects of drinking hydrogen-rich water for six weeks on exercise-related biomarkers in exercise-naïve men and women over 50 years following resistance training program: a randomized controlled pilot trial.
Jovan Kuzmanovic, Nikola Todorovic, Marijana Ranisavljev, Dejan Javorac, Darinka Korovljev, Alex Tarnava, Valdemar Stajer, Sergej M Ostojic · Research in sports medicine (Print) · 2025
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In 27 apparently healthy, middle-aged participants (18 women), HRW significantly outperformed the control water in reducing biomarkers of acute muscular damage caused by resistance exercise (p ≤ 0.05); the sleep quality difference favored HRW but was not statistically significant (p = 0.119). These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence sleep-related outcomes.
What the Findings Mean
H2HUBB reviewed how hydrogen-rich water affected the outcomes measured in 27 apparently healthy, middle-aged participants (18 women). HRW significantly outperformed the control water in reducing biomarkers of acute muscular damage caused by resistance exercise (p ≤ 0.05); the sleep quality difference favored HRW but was not statistically significant (p = 0.119).
What the Researchers Studied
The researchers studied 27 apparently healthy, middle-aged participants (18 women). The study used a randomized, double-blind, placebo-controlled human clinical trial. The comparison condition was placebo.
What Effects Did Molecular Hydrogen Have?
HRW significantly outperformed the control water in reducing biomarkers of acute muscular damage caused by resistance exercise (p ≤ 0.05); the sleep quality difference favored HRW but was not statistically significant (p = 0.119).
Why These Findings Matter
These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence sleep-related outcomes and contribute to the growing body of molecular-hydrogen research.
How Strong Is This Evidence?
This is human clinical evidence from a randomized, double-blind, placebo-controlled human clinical trial. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.
Technical Study Details
H2HUBB classifies this publication as human clinical study with human clinical evidence. The research population or model was 27 apparently healthy, middle-aged participants (18 women). The reported sample size was 18. The study used a randomized, double-blind, placebo-controlled human clinical trial. The hydrogen delivery method was hydrogen-rich water. The reported hydrogen concentration was 0.1 mg/L H₂.
Limitations and Safety
No separate limitations or safety findings were identified in the source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.