The effects of drinking hydrogen-rich water for six weeks on exercise-related biomarkers in exercise-naïve men and women over 50 years following resistance training program: a randomized controlled pilot trial.
Jovan Kuzmanovic, Nikola Todorovic, Marijana Ranisavljev, Dejan Javorac, Darinka Korovljev, Alex Tarnava, Valdemar Stajer, Sergej M Ostojic · Research in sports medicine (Print) · 2025
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
Muscle performance indices showed a significant improvement following both HRW and control water interventions compared to the baseline values. This pilot study suggests therapeutic potential, while larger randomized, placebo-controlled studies are needed to confirm the finding.
What the Researchers Studied
The study examined 27 apparently healthy, middle-aged participants (18 women).
How Molecular Hydrogen Was Used
All participants were allocated in a double-blind parallel-group design to receive either HRW (12 mg of dihydrogen per serving) or control water (<0.1 ppm of dihydrogen) administered two times per day during a 6-week intervention interval.
What the Researchers Found
HRW significantly outperformed the control water in reducing biomarkers of acute muscular damage caused by resistance exercise (p ≤ 0.05); the sleep quality difference favored HRW but was not statistically significant (p = 0.119). Muscle performance indices showed a significant improvement following both HRW and control water interventions compared to the baseline values (p ≤ 0.05).
H₂ Mechanisms / Biological Findings
The source material reviewed did not establish a specific molecular hydrogen mechanism for the reported findings.
Authors’ Conclusion
A distinct authors’ conclusion was not available in the source material reviewed by H2HUBB.