The impact of perioperative hydrogen gas inhalation on postoperative recovery in day surgery patients: a research study.
Shuman Ji, Qianqian Xiao, Bohua Zhang, Runlu Cai, Yayu Jing, Duomin Yang, Ni Liu, Zhanqin Zhang, Xiaopeng Mei · Scientific reports · 2026
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In exploratory analyses, the hydrogen group also showed descriptive trends toward lower pain scores, greater physical independence, and improved sleep quality. These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence inflammatory regulation.
What the Findings Mean
H2HUBB reviewed how molecular hydrogen affected the outcomes measured in 150 patients with 76 in the hydrogen group and 74 in the control group. In exploratory analyses, the hydrogen group also showed descriptive trends toward lower pain scores, greater physical independence, and improved sleep quality.
What the Researchers Studied
The researchers studied 150 patients with 76 in the hydrogen group and 74 in the control group. The study used a randomized, double-blind human clinical trial. The comparison condition was control condition or baseline measurements.
What Effects Did Molecular Hydrogen Have?
66.7% inhaled H₂ concentration. In exploratory analyses, the hydrogen group also showed descriptive trends toward lower pain scores, greater physical independence, and improved sleep quality. The authors concluded that perioperative hydrogen inhalation may alleviate inflammatory stress and promote recovery in patients undergoing day surgery.
Why These Findings Matter
These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence inflammatory regulation and contribute to the growing body of molecular-hydrogen research.
How Strong Is This Evidence?
This is human clinical evidence from a randomized, double-blind human clinical trial. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.
Technical Study Details
H2HUBB classifies this publication as human clinical study with human clinical evidence. The research population or model was 150 patients with 76 in the hydrogen group and 74 in the control group. The reported sample size was 150. The study used a randomized, double-blind human clinical trial. The reported hydrogen concentration was 66.7% inhaled H₂ concentration.
Limitations and Safety
No separate limitations or safety findings were identified in the source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.