Two-week continuous supplementation of hydrogenrich water increases peak oxygen uptake during an incremental cycling exercise test in healthy humans: a randomized, single-blinded, placebo-controlled study.
Amane Hori, Sayaka Sobue, Ryosuke Kurokawa, Shin-Ichi Hirano, Masatoshi Ichihara, Norio Hotta · Medical gas research · 2020
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In conclusion, the continuous supplementation of HW potentially augments the aerobic capacity, implying that continuous supplementation of H₂ might help improve aerobic exercise performance and physical health. These findings add human evidence that helps define the outcomes that did and did not change with molecular hydrogen in this study.
What the Findings Mean
H2HUBB reviewed how hydrogen-rich water affected the outcomes measured in In this randomized, single-blinded, placebo-controlled experimental study, the participants performed an incremental cycling exercise to measure peak oxygen uptake and peak load before and after a sin. In conclusion, the continuous supplementation of HW potentially augments the aerobic capacity, implying that continuous supplementation of H₂ might help improve aerobic exercise performance and physical health.
What the Researchers Studied
The researchers studied In this randomized, single-blinded, placebo-controlled experimental study, the participants performed an incremental cycling exercise to measure peak oxygen uptake and peak load before and after a sin. The study used a randomized, placebo-controlled human clinical trial. The comparison condition was placebo.
What Effects Did Molecular Hydrogen Have?
Source-reported hydrogen exposure: 500 mL hydrogen-rich water per reported dose; dissolved H₂ concentration was not sufficiently reported, so H2HUBB did not estimate milligrams of H₂. In conclusion, the continuous supplementation of HW potentially augments the aerobic capacity, implying that continuous supplementation of H₂ might help improve aerobic exercise performance and physical health. BAP: Biological antioxidant potential, which is an index of antioxidant activity; d-ROMs: diacron reactive oxygen metabolites, which is an index of oxidative stress level; HW: hydrogen-rich water; PW: placebo water.
Why These Findings Matter
This publication adds useful evidence about where molecular hydrogen did and did not change the measured outcomes, helping define the larger therapeutic evidence base.
How Strong Is This Evidence?
This is human clinical evidence from a randomized, placebo-controlled human clinical trial. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.
Technical Study Details
H2HUBB classifies this publication as human clinical study with human clinical evidence. The research population or model was In this randomized, single-blinded, placebo-controlled experimental study, the participants performed an incremental cycling exercise to measure peak oxygen uptake and peak load before and after a sin. The reported sample size was 6. The study used a randomized, placebo-controlled human clinical trial. The hydrogen delivery method was hydrogen-rich water. The source-reported hydrogen exposure was 500 mL hydrogen-rich water per reported dose; dissolved H₂ concentration was not sufficiently reported, so H2HUBB did not estimate milligrams of H₂.
Limitations and Safety
Safety information: 11 H₂ has a safety advantage as it is not cytotoxic, even at high concentrations.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.