Magnesium-Based Micromotors as Hydrogen Generators for Precise Rheumatoid Arthritis Therapy.
This animal study examined Magnesium-Based Micromotors as Hydrogen Generators for Precise Rheumatoid Arthritis Therapy. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: However, nonpolarity and low solubility of hydrogen under the physiological conditions results in a limited therapeutic effect. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β Signaling Pathway in Rats.
This animal study examined Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β Signaling Pathway in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The PI3K/Akt/GSK3β signaling pathway plays an important role in the mechanism of CPB-induced brain injury. HRS can reduce CPB-induced brain injury and inhibit CMEC…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhibitory Effects of Hydrogen on Proliferation and Migration of Vascular Smooth Muscle Cells via Down-Regulation of Mitogen/Activated Protein Kinase and Ezrin-Radixin-Moesin Signaling Pathways.
This animal study examined Inhibitory Effects of Hydrogen on Proliferation and Migration of Vascular Smooth Muscle Cells via Down-Regulation of Mitogen/Activated Protein Kinase and Ezrin-Radixin-Moesin Signaling Pathways. The abstract describes Animal model; hydrogen delivered as injected or infused hydrogen; reported duration 6 weeks. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus-activated kinase 2/signal transducer and activator of transcription 3 signaling pathway.
This animal study examined Hydrogen-rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus-activated kinase 2/signal transducer and activator of transcription 3 signaling pathway. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: The HRS treatment resulted in the significant upregulation of malonyl dialdehyde (MDA) and myeloperoxidase (MPO), whilesuperoxide dismutase (SOD) levels were significantly downregulated, compared with…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read More[Effect of hydrogen-rich saline on blood pressure and antioxidant ability of lung tissue in scalded rats following delayed resuscitation].
This animal study examined [Effect of hydrogen-rich saline on blood pressure and antioxidant ability of lung tissue in scalded rats following delayed resuscitation]. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Delayed resuscitation for scalded rats with hydrogen-rich saline is helpful in the recovery of systolic pressure, and it can ameliorate lung tissue injury caused…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen saline offers neuroprotection by reducing oxidative stress in a focal cerebral ischemia-reperfusion rat model
This animal study examined Hydrogen saline offers neuroprotection by reducing oxidative stress in a focal cerebral ischemia-reperfusion rat model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These findings demonstrated hydrogen saline is neuroprotective when administered within 6 h after ischemia. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of intravenous infusion of hydrogen-rich fluid combined with intra-cisternal infusion of magnesium sulfate in severe aneurysmal subarachnoid hemorrhage: study protocol for a randomized controlled trial.
This study protocol examined Effects of intravenous infusion of hydrogen-rich fluid combined with intra-cisternal infusion of magnesium sulfate in severe aneurysmal subarachnoid hemorrhage: study protocol for a randomized controlled trial. The abstract describes Planned or registered research population; sample size 450; hydrogen delivered as injected or infused hydrogen. The abstract reports: Recent accumulating evidence has suggested that early brain injury is also involved in the development of delayed cerebral ischemia, and that hydrogen can prevent…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreIntravenous Hydrogen Therapy With Intracisternal Magnesium Sulfate Infusion in Severe Aneurysmal Subarachnoid Hemorrhage
This randomized controlled trial examined Intravenous Hydrogen Therapy With Intracisternal Magnesium Sulfate Infusion in Severe Aneurysmal Subarachnoid Hemorrhage. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen; reported duration 14 days. The abstract reports: Intracisternal magnesium sulfate infusion started immediately after surgery reduces the incidence of cerebral vasospasm and delayed cerebral ischemia and improves clinical outcomes without complications…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline injection into the subarachnoid cavity within 2 weeks promotes recovery after acute spinal cord injury.
This animal study examined Hydrogen-rich saline injection into the subarachnoid cavity within 2 weeks promotes recovery after acute spinal cord injury. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 2 weeks. The abstract reports: Results at 24 hours, 48 hours, 1 week and 2 weeks after injury showed that hydrogen-rich saline markedly reduced cell death, inflammatory cell infiltration,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice.
This animal study examined Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice. The abstract describes Mouse model; sample size 1; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Activation of mast cells following intracerebral hemorrhage contributed to increase of blood-brain barrier permeability and brain edema. Hydrogen inhalation preserved blood-brain barrier disruption by…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model.
This animal study examined Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: H gas administration exerted a neuroprotective effect against early brain injury after ICH through anti-inflammatory, neuroprotective, anti-apoptotic, and antioxidative activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage.
This animal study examined Hydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Our results suggest that hydrogen inhalation exerts an acute brain-protective effect in the mouse ICH model. However, the acute hydrogen therapy alone is not…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline improves survival and neurological outcome after cardiac arrest and cardiopulmonary resuscitation in rats.
This uncontrolled human study examined Hydrogen-rich saline improves survival and neurological outcome after cardiac arrest and cardiopulmonary resuscitation in rats. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline treatment improved survival and neurological outcome after cardiac arrest/resuscitation in rats, which was partially mediated by reducing oxidative stress, inflammation, and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe neuroprotective effects of intraperitoneal injection of hydrogen in rabbits with cardiac arrest.
This animal study examined The neuroprotective effects of intraperitoneal injection of hydrogen in rabbits with cardiac arrest. The abstract describes Rabbit model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Intraperitoneal injection of H2 is a novel hydrogen administration method and can reduce cerebral ischemia-reperfusion injury and improve the prognosis of cardiopulmonary cerebral resuscitation…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress.
This uncontrolled human study examined Protective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline can exert a protective effect against TBI via reducing oxidative stress. Molecular hydrogen may be a more effective therapeutic strategy for TBI…. This is an automated editorial draft based on the abstract and requires source review before publication.
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