Local Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway.
This animal study examined Local Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results showed that local treatment of hydrogen-rich saline shortened wound closure time and reduced the level of proinflammatory cytokines and lipid peroxidation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA review of experimental studies of hydrogen as a new therapeutic agent in emergency and critical care medicine.
This narrative review examined A review of experimental studies of hydrogen as a new therapeutic agent in emergency and critical care medicine. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen-rich saline and hydrogen bath and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePharmacokinetics of hydrogen administered intraperitoneally as hydrogen-rich saline and its effect on ischemic neuronal cell death in the brain in gerbils.
This in vitro or cellular study examined Pharmacokinetics of hydrogen administered intraperitoneally as hydrogen-rich saline and its effect on ischemic neuronal cell death in the brain in gerbils. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Intraperitoneal administration of H2-rich saline resulted in large increases in H2 concentration in the IVC ranging from 0.00183 mg/L (0.114%) to 0.00725 mg/L (0.453%). This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen‐rich and hyperoxygenate saline inhibits lipopolysaccharide‐induced lung injury through mediating NF‐κB/NLRP3 signaling pathway in C57BL/6 mice
This animal study examined Hydrogen‐rich and hyperoxygenate saline inhibits lipopolysaccharide‐induced lung injury through mediating NF‐κB/NLRP3 signaling pathway in C57BL/6 mice. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Hydrogen plays a more important role in the inflammatory and anti-apoptosis mechanisms, while oxygen improves hypoxia of the body, and thus, its molecular mechanism…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSafety of intravenous administration of hydrogen-enriched fluid in patients with acute cerebral ischemia: initial clinical studies.
This uncontrolled human study examined Safety of intravenous administration of hydrogen-enriched fluid in patients with acute cerebral ischemia: initial clinical studies. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen. The abstract reports: Data from the current study indicate that an H2-enriched intravenous solution is safe for patients with acute cerebral infarction, including patients treated with t-PA. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs.
This animal study examined Pharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen: Emerging Treatment for Stroke Management
This narrative review examined Molecular Hydrogen: Emerging Treatment for Stroke Management. The abstract describes Published literature review; hydrogen delivered as injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePharmacokinetics of hydrogen after ingesting a hydrogen-rich solution: A study in pigs.
This animal study examined Pharmacokinetics of hydrogen after ingesting a hydrogen-rich solution: A study in pigs. The abstract describes Animal model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 120 min. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline inhibits tobacco smoke-induced chronic obstructive pulmonary disease by alleviating airway inflammation and mucus hypersecretion in rats.
This animal study examined Hydrogen-rich saline inhibits tobacco smoke-induced chronic obstructive pulmonary disease by alleviating airway inflammation and mucus hypersecretion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 12 weeks. The abstract reports: ELISA assay showed hydrogen-rich saline lowered the levels of pro-inflammatory cytokines (IL-8 and IL-6) and anti-inflammatory cytokine IL-10 in bronchoalveolar lavage fluid and serum…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice.
This animal study examined Hydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Molecular hydrogen exhibited a protective effect on the LIR-induced ALI model. Hydrogen decreased malondialdehyde and increased superoxide dismutase activity in lung tissues. Additionally, hydrogen…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEvaluation of the therapeutic effects of nebulized inhalation of hydrogen-rich water on primary blast lung injury in C57BL/6 mice.
This animal study examined Evaluation of the therapeutic effects of nebulized inhalation of hydrogen-rich water on primary blast lung injury in C57BL/6 mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: The overpressure generated by blasts leads to alveolar and capillary damage, resulting in ventilation-perfusion mismatch and increased intrapulmonary shunting. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of hydrogen water reduces paraquat-induced acute lung injury in rats.
This animal study examined Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results showed that hydrogen water ameliorated these alterations, demonstrating that hydrogen water alleviated paraquat-induced acute lung injury possibly by inhibition of oxidative damage. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of molecular hydrogen on lung injury from lung transplantation
This narrative review examined Protective effects of molecular hydrogen on lung injury from lung transplantation. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The reviewed studies showed that H improved the outcomes of lung transplantation by decreasing oxidative stress and inflammation at the donor and recipient phases. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation.
This animal study examined Protective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: The use of a hydrogen-rich preservation solution attenuates ischemia-reperfusion injury in rat lungs during cold ischemia through antioxidant and anti-inflammatory effects. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAttenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival.
This animal study examined Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The study highlights that continuous inhalation of hydrogen gas at a 2 % concentration for 24 h can be a potent intervention in the geriatric population…. This is an automated editorial draft based on the abstract and requires source review before publication.
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